THE ROLE OF LABORATORY EXAMINATION IN RED EYE SYNDROME

• Published in: Alʹmanakh klinicheskoĭ medit͡s︡iny no. 36; pp. 59 - 66
• Main Authors: Chernakova, G. M., Kleshcheva, E. A., Obrubov, A. S., Ovsyanko, A. A., Semenova, T. B.
• Format: Journal Article
• Language: English; Russian
• Published: MONIKI 21-02-2016
• Subjects: conjunctivitis; herpesviruses; keratitis; laboratory diagnostics; red eye syndrome; ureaplasma
• DOI: 10.18786/2072-0505-2015-36-59-66
• EISSN: 2587-9294
• ISSN: 2072-0505

Aim: To analyze etiological structure of inflammatory diseases of ocular surface. Materials and methods: The study included outpatients (n = 49) who referred to Ophthalmological office at the Herpetic center during the period 2012 to 2014. Complaints duration was 60.65 ± 12.28 days. All patients underwent routine ophthalmologic examination; tear and/or conjunctival scraping PCR for type 1 and 2 herpes simplex viruses, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus, type 6 human herpesvirus, adenoviruses, enteroviruses, ureaplasma, chlamydia; conjunctival swab microbiology; eyelash microscopy for eyelash mites. Results: After the examination, all patients were divided into three groups: 1) with herpesvirus infections of the eye (n = 24), 2) with non-herpetic infection of the eye (enterovirus, adenovirus, bacteria, fungi, n = 18), 3) with ocular surface lesions due to non-infectious causes (n = 7). In three cases U. urealyticum was detected, doxycycline was administrated. Identification of pathogens in the groups 1 and 2 resulted in effective causal treatment with subsequent clinical recovery. Exclusion of infection in the third group allowed to avoid inappropriate antibacterial or antiviral therapy. Conclusion: In patients with chronic red eye syndrome of unknown etiology, laboratory examination of tear and/or conjunctival scraping is essential for differentiating between infectious and non-infectious disease.