Takotsubo Cardiomyopathy: Its Possible Impact during Adult Donor Care

Takotsubo cardiomyopathy, the syndrome caused by an extreme release and circulation of catecholamines, shares several histopathological and clinical similarities with cardiac changes after brain death noted in animal investigations and human observation. Overwhelming stimulation of myocardial inotro...

Full description

Saved in:

Bibliographic Details
Published in:	Progress in transplantation (Aliso Viejo, Calif.) Vol. 21; no. 4; pp. 344 - 349
Main Authors:	Powner, David J., Truong, Hanh
Format:	Journal Article
Language:	English
Published:	Los Angeles, CA SAGE Publications 01-12-2011 SAGE PUBLICATIONS, INC
Subjects:	Adult Cardiovascular Agents - therapeutic use Echocardiography Extracorporeal Membrane Oxygenation Humans Takotsubo Cardiomyopathy - diagnostic imaging Takotsubo Cardiomyopathy - physiopathology Takotsubo Cardiomyopathy - therapy Tissue Donors
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Takotsubo cardiomyopathy, the syndrome caused by an extreme release and circulation of catecholamines, shares several histopathological and clinical similarities with cardiac changes after brain death noted in animal investigations and human observation. Overwhelming stimulation of myocardial inotropic β receptors may alter their responsiveness and induce other biochemical processes, producing reduced cardiac contractility. Treatment methods in Takotsubo cardiomyopathy that use extracorporeal circulatory support and medications that do not rely on β-receptor stimulation and preemptive blockade of β receptors or calcium channels before brain death may be relevant to donor care.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1526-9248 2164-6708
DOI:	10.1177/152692481102100415