Genetic factors in the development of pulmonary embolism

Genetic factors in the development of pulmonary embolism

The article presents a literature review on the study of the relationship of FGA, FGB, F2, F5, PAI, ITGA2 gene polymorphisms with the development of pulmonary embolism (PE). We concluded that genetic factors in the development of PE are to a greater extent mutations in the F2, F5, PAI, ITGA2 genes....

Full description

Saved in:
Bibliographic Details
Published in:Rossiĭskiĭ kardiologicheskiĭ zhurnal Vol. 27; no. 10; p. 5173
Main Authors: Kryuchkova, N. M., Chernova, A. A., Nikulina, S. Yu, Maksimov, V. N.
Format: Journal Article
Language:English
Russian
Published: FIRMA «SILICEA» LLC 01-11-2022
Subjects:
factor v leiden mutation
gene
genotype
itga2
pai
polymorphism
pulmonary embolism
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The article presents a literature review on the study of the relationship of FGA, FGB, F2, F5, PAI, ITGA2 gene polymorphisms with the development of pulmonary embolism (PE). We concluded that genetic factors in the development of PE are to a greater extent mutations in the F2, F5, PAI, ITGA2 genes. There is a positive correlation between the presence of combined genetic mutations and the development of PE. The study of allelic polymorphism of hemostasis genes makes it possible to predict coagulation system disorders, including PE.
ISSN:1560-4071
2618-7620
DOI:10.15829/1560-4071-2022-5173