Association of Lesions and the Pathogenesis of Anosognosia in Hemiplegia in Cases Involving Neither Somatosensory Disturbance nor Unilateral Spatial Neglect

• Published in: Rigaku ryoho kagaku Vol. 36; no. 1; pp. 101 - 106
• Main Authors: SASAKI, Tomo, MAEDA, Masaharu
• Format: Journal Article
• Language: English; Japanese
• Published: Tokyo The Society of Physical Therapy Science 2021; Japan Science and Technology Agency
• Subjects: anosognosia for hemiplegia; associated loop; Neurological disorders; Paralysis; Pathogenesis
• ISSN: 1341-1667; 2434-2807
• DOI: 10.1589/rika.36.101

[Purpose] The purpose of this research was to investigate the pathogenesis of anosognosia in hemiplegia (AHP) by focusing on somatosensory disturbance and unilateral spatial neglect (USN) which are considered to be associated with AHP. [Participants and Methods] Three case reports and an author’s case were the subjects of this study. The pathogenesis of AHP was investigated by focusing on lesion and the presence of somatosensory disturbance and USN. [Results] We consider that the dorsolateral prefrontal cortex (DLPFC) and the putamen/globus pallidus, which were both common lesions of the neither somatosensory disturbance nor unilateral spatial neglect (NSU) group, are associated with the pathogenesis of AHP. [Conclusion] As the DLPFC is associated with self-monitoring and the putamen/globus pallidus is associated with components of executive function, we consider that functional disturbance in the associated loop is a factor that triggered the pathogenesis of AHP in the NSU group.