Dengue: inquérito sorológico pós-epidêmico em zona urbana do Estado de São Paulo (Brasil)
OBJETIVO: Avaliar o tamanho real da epidemia sobre dengue ocorrida na zona urbana do Município de Santa Bárbara D'Oeste, SP, Brasil, de abril a junho de 1995. MÉTODOS: Foi realizado um inquérito soroepidemiológico pós-epidêmico 5 meses após o final da epidemia da dengue. Foram processados 1.113...
Saved in:
Published in: | Revista de saúde pública Vol. 33; no. 6; pp. 566 - 574 |
---|---|
Main Authors: | , , , , , , , , |
Format: | Journal Article |
Language: | English |
Published: |
01-12-1999
|
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Abstract | OBJETIVO: Avaliar o tamanho real da epidemia sobre dengue ocorrida na zona urbana do Município de Santa Bárbara D'Oeste, SP, Brasil, de abril a junho de 1995. MÉTODOS: Foi realizado um inquérito soroepidemiológico pós-epidêmico 5 meses após o final da epidemia da dengue. Foram processados 1.113 soros através de amostragem aleatória domiciliar da população da cidade pesquisada. As taxas de infecção em diferentes partes da cidade foram relacionadas com os graus de infestação por Aedes aegipty e com a quantidade de casos notificados durante a epidemia. RESULTADOS E CONCLUSÕES: Foi encontrada variação concomitante e diretamente proporcional entre as taxas de infecção pelo vírus da dengue, em diferentes partes da cidade, e os graus de infestação domiciliar por Aedes aegipty, bem como em relação ao número de casos notificados durante a epidemia. Encontrou-se prevalência de 630 por 100 mil habitantes, representando valor 15 vezes superior ao de incidência de casos confirmados laboratorialmente durante a epidemia. Através de comparação retrospectiva com dados de notificação compulsória, observou-se que a vigilância epidemiológica não detectou a maioria das pessoas soro-reativas. Apesar disso, notificou grande quantidade de casos que não eram de indivíduos com dengue, tipificando um valor preditivo positivo baixo (15,6%) para o diagnóstico clínico de dengue quando o resultado laboratorial (HAI) é tomado como padrão-ouro.
OBJECTIVE: The objective of this study was to evaluate the real size of the epidemics registered in the urban area of the county of Santa Bárbara D'Oeste, SP, Brazil, from April to June, 1995. The measurement of the epidemiological validity of the official surveillance system criteria and its positive predicted value were adopted as specific goals. METHODS: A sero-epidemiological survey was carried out over a sample of 1,113 sera from citizens of Santa Barbara D'Oeste, through a systematic random sampling of houses, five months after the end of the epidemics. Infection rates were compared with the infestation indexes by Aedes aegipty and the notified cases amongst the county sections. The importance of submitting patients with clinical suspicion of dengue to laboratory tests was discussed. RESULTS AND DISCUSSION: It was found that infection rates by dengue virus varied in the same direction and proportion as the presence of Aedes aegipty larvae reported by the "Breteau Index", as well as the number of cases reported by the official notifiable diseases surveillance system during the epidemics. A prevalence of 630 by 100 thousand inhabitants was found, a 15-fold rate when compared to the laboratory positive sera from cases detected by the surveillance system during the epidemics. A retrospective comparison with the surveillance reports, using serological results as a gold standard, also showed that the majority of dengue specific serum-positive individuals were not detected during the epidemics, otherwise cases that did not present serological reaction were notified exhibiting a low positive predictive value of clinical diagnosis (15,6). |
---|---|
AbstractList | OBJETIVO: Avaliar o tamanho real da epidemia sobre dengue ocorrida na zona urbana do Município de Santa Bárbara D'Oeste, SP, Brasil, de abril a junho de 1995. MÉTODOS: Foi realizado um inquérito soroepidemiológico pós-epidêmico 5 meses após o final da epidemia da dengue. Foram processados 1.113 soros através de amostragem aleatória domiciliar da população da cidade pesquisada. As taxas de infecção em diferentes partes da cidade foram relacionadas com os graus de infestação por Aedes aegipty e com a quantidade de casos notificados durante a epidemia. RESULTADOS E CONCLUSÕES: Foi encontrada variação concomitante e diretamente proporcional entre as taxas de infecção pelo vírus da dengue, em diferentes partes da cidade, e os graus de infestação domiciliar por Aedes aegipty, bem como em relação ao número de casos notificados durante a epidemia. Encontrou-se prevalência de 630 por 100 mil habitantes, representando valor 15 vezes superior ao de incidência de casos confirmados laboratorialmente durante a epidemia. Através de comparação retrospectiva com dados de notificação compulsória, observou-se que a vigilância epidemiológica não detectou a maioria das pessoas soro-reativas. Apesar disso, notificou grande quantidade de casos que não eram de indivíduos com dengue, tipificando um valor preditivo positivo baixo (15,6%) para o diagnóstico clínico de dengue quando o resultado laboratorial (HAI) é tomado como padrão-ouro.
OBJECTIVE: The objective of this study was to evaluate the real size of the epidemics registered in the urban area of the county of Santa Bárbara D'Oeste, SP, Brazil, from April to June, 1995. The measurement of the epidemiological validity of the official surveillance system criteria and its positive predicted value were adopted as specific goals. METHODS: A sero-epidemiological survey was carried out over a sample of 1,113 sera from citizens of Santa Barbara D'Oeste, through a systematic random sampling of houses, five months after the end of the epidemics. Infection rates were compared with the infestation indexes by Aedes aegipty and the notified cases amongst the county sections. The importance of submitting patients with clinical suspicion of dengue to laboratory tests was discussed. RESULTS AND DISCUSSION: It was found that infection rates by dengue virus varied in the same direction and proportion as the presence of Aedes aegipty larvae reported by the "Breteau Index", as well as the number of cases reported by the official notifiable diseases surveillance system during the epidemics. A prevalence of 630 by 100 thousand inhabitants was found, a 15-fold rate when compared to the laboratory positive sera from cases detected by the surveillance system during the epidemics. A retrospective comparison with the surveillance reports, using serological results as a gold standard, also showed that the majority of dengue specific serum-positive individuals were not detected during the epidemics, otherwise cases that did not present serological reaction were notified exhibiting a low positive predictive value of clinical diagnosis (15,6). |
Author | Rangel, Osias Lima, Virgília L C de Correa F, Heleno R Leite, Odair F Vido, Alessandra A Carlucci, Rita H Owa, Miyoco A Figueiredo, Luiz T M Oliveira, Susely S |
Author_xml | – sequence: 1 givenname: Virgília L C de surname: Lima fullname: Lima, Virgília L C de organization: Superintendência de Controle de Endemias, Brasil – sequence: 2 givenname: Luiz T M surname: Figueiredo fullname: Figueiredo, Luiz T M organization: Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo, Brasil – sequence: 3 givenname: Heleno R surname: Correa F fullname: Correa F, Heleno R organization: Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo, Brasil – sequence: 4 givenname: Odair F surname: Leite fullname: Leite, Odair F organization: Superintendência de Controle de Endemias, Brasil – sequence: 5 givenname: Osias surname: Rangel fullname: Rangel, Osias organization: Superintendência de Controle de Endemias, Brasil – sequence: 6 givenname: Alessandra A surname: Vido fullname: Vido, Alessandra A organization: Superintendência de Controle de Endemias, Brasil – sequence: 7 givenname: Susely S surname: Oliveira fullname: Oliveira, Susely S organization: Superintendência de Controle de Endemias, Brasil – sequence: 8 givenname: Miyoco A surname: Owa fullname: Owa, Miyoco A organization: Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo, Brasil – sequence: 9 givenname: Rita H surname: Carlucci fullname: Carlucci, Rita H organization: Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo, Brasil |
BookMark | eNplkE1OwzAQRi1UJNrCGfASFoGxncQ2O2jLj1QJpMKWyHGcyiiJi90s4DqsYNsj5GKkgBASi9GbTzMajd4IDRrXGIQOCZyQRMLpAoDFkZAEiJQSANK-QOyg4e9g8KffQ6MQngAoo0wM0ePUNMvWnGHbPLfdu7drh4Pzruo2S6sdXnWbEJmVLbqPeptNjV9do3Drc9WjcHgW1qpHYfCie3P4TrWVw0cXXgVbHe-j3VJVwRz8cIweLmf3k-tofnt1MzmfR5okREQ8ToHJlMZx2b-f6JLHJFdUJIRrxbjhlGsjaZlCLspEcsE19AuCM0WZ1jEbI_59V3sXgjdltvK2Vv4lI5BtNWVfmrJ_mtgniTVezg |
CitedBy_id | crossref_primary_10_1590_S0037_86822007000200009 crossref_primary_10_1590_S0103_73312011000100011 crossref_primary_10_1016_j_actatropica_2016_02_003 crossref_primary_10_1111_tmi_13061 crossref_primary_10_1186_s12879_019_4074_4 crossref_primary_10_1590_1806_9282_63_05_447 crossref_primary_10_1590_1980_549720210020 crossref_primary_10_1017_S0007485316001115 crossref_primary_10_1590_S0102_311X2007000300025 crossref_primary_10_1016_j_jviromet_2012_09_012 crossref_primary_10_1371_journal_pntd_0002873 crossref_primary_10_1590_S0034_89102002000200007 |
Cites_doi | 10.1590/S0034-89101986000300003 10.1590/S0034-89101991000400003 10.4269/ajtmh.1987.36.153 10.4269/ajtmh.1990.42.179 |
ContentType | Journal Article |
DBID | AAYXX CITATION |
DOI | 10.1590/S0034-89101999000600008 |
DatabaseName | CrossRef |
DatabaseTitle | CrossRef |
DatabaseTitleList | CrossRef |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Public Health |
EISSN | 0034-8910 |
EndPage | 574 |
ExternalDocumentID | 10_1590_S0034_89101999000600008 |
GroupedDBID | 123 29P 2WC 53G 5VS AAYXX ABXHO ACHQT ADBBV ADRAZ AENEX ALMA_UNASSIGNED_HOLDINGS AOIJS APOWU AZFZN BAWUL BCNDV CITATION DIK DU5 E3Z F5P GROUPED_DOAJ GX1 HYE IPNFZ KQ8 M48 M~E OK1 P2P PGMZT RIG RNS RPM RSC RSL SCD XSB |
ID | FETCH-LOGICAL-c1518-7460396244f0605cf741ba28517ca37e727ce92f60b8f59787c01ba873a23cc43 |
ISSN | 0034-8910 |
IngestDate | Thu Nov 21 21:46:36 EST 2024 |
IsDoiOpenAccess | false |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 6 |
Language | English |
LinkModel | OpenURL |
MergedId | FETCHMERGED-LOGICAL-c1518-7460396244f0605cf741ba28517ca37e727ce92f60b8f59787c01ba873a23cc43 |
OpenAccessLink | https://www.scielo.br/j/rsp/a/HbqvpWzMhfv6p9wvppYzwRC/?lang=pt&format=pdf |
PageCount | 9 |
ParticipantIDs | crossref_primary_10_1590_S0034_89101999000600008 |
PublicationCentury | 1900 |
PublicationDate | 1999-12-00 |
PublicationDateYYYYMMDD | 1999-12-01 |
PublicationDate_xml | – month: 12 year: 1999 text: 1999-12-00 |
PublicationDecade | 1990 |
PublicationTitle | Revista de saúde pública |
PublicationYear | 1999 |
References | (ref12) 1997; 18 (ref14) 1997; 6 Figueiredo LTM (ref5) Theiler M (ref15) 1973 Alves MCGP (ref1) 1991; 25 Figueiredo LTM (ref4) 1986; 20 Tirado MGG (ref16) 1984; 36 Johnson KM (ref9) 1967; 9 Shope RE (ref13) 1979 Guzmán MG (ref7) 1990; 42 Dietz VJ (ref3) 1990; 131 Halstead SP (ref8) 1990; 21 (ref11) 1987 Figueiredo LTM (ref6) 1995; 118 Kuno G (ref10) 1987; 36 (ref2) 1996; 11 |
References_xml | – volume: 21 start-page: 636 issn: 0038-3619 year: 1990 ident: ref8 article-title: Global epidemiology of dengue hemorrhagic fever publication-title: Southeast Asian J Trop Med Public Health contributor: fullname: Halstead SP – volume: 131 start-page: 693 issn: 0002-9262 year: 1990 ident: ref3 article-title: Epidemic dengue 1 in Brazil, 1986: evaluation of a clinically based dengue surveillance system publication-title: Am J Epidemiol contributor: fullname: Dietz VJ – volume: 6 issue: 1 year: 1997 ident: ref14 publication-title: Inf Epidemiol SUS – volume: 20 start-page: 204 year: 1986 ident: ref4 article-title: Níveis de anticorpos para arbovírus em indivíduos da região de Ribeirão Preto, SP (Brasil) publication-title: Rev Saúde Pública doi: 10.1590/S0034-89101986000300003 contributor: fullname: Figueiredo LTM – year: 1987 ident: ref11 – start-page: 62 year: 1973 ident: ref15 contributor: fullname: Theiler M – volume: 25 start-page: 251 year: 1991 ident: ref1 article-title: Plano amostral para cálculo de densidade larvária de Aedes aegypti e Aaedes albopictus no Estado de São Paulo, Brasil publication-title: Rev Saúde Pública doi: 10.1590/S0034-89101991000400003 contributor: fullname: Alves MCGP – volume: 9 start-page: 105 issn: 0079-645X year: 1967 ident: ref9 article-title: Hemorrhagic fever of Southeast Asia and South America: a comparative appraisal publication-title: Prog Med Virol contributor: fullname: Johnson KM – volume: 118 start-page: 499 issn: 0030-0632 year: 1995 ident: ref6 article-title: Encuesta serológica sobre el dengue en Ribeirão Preto, São Paulo, Brasil publication-title: Bol Oficina Sanit Panam contributor: fullname: Figueiredo LTM – volume: 36 start-page: 153 issn: 0002-9637 year: 1987 ident: ref10 article-title: Detecting artificial anti-dengue IgM immune complexes using an enzyme-linked immunosorbent assay publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.1987.36.153 contributor: fullname: Kuno G – start-page: 767 volume-title: Arboviruses year: 1979 ident: ref13 contributor: fullname: Shope RE – volume: 36 start-page: 124 year: 1984 ident: ref16 article-title: Encuesta serológica nacional a virus dengue. Cuba 1982 publication-title: Rev Cub Med Trop contributor: fullname: Tirado MGG – ident: ref5 contributor: fullname: Figueiredo LTM – volume: 42 start-page: 179 issn: 0002-9637 year: 1990 ident: ref7 article-title: Dengue hemorrhagic fever in Cuba, 1981: a retrospective seroepidemiologic study publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.1990.42.179 contributor: fullname: Guzmán MG – volume: 18 issn: 0374-6119 issue: 2 year: 1997 ident: ref12 article-title: Resurgimiento del dengue en las Américas publication-title: Bol Epidemiol – volume: 11 issue: 47 year: 1996 ident: ref2 publication-title: Bol Inform |
SSID | ssj0023238 |
Score | 1.5590934 |
Snippet | OBJETIVO: Avaliar o tamanho real da epidemia sobre dengue ocorrida na zona urbana do Município de Santa Bárbara D'Oeste, SP, Brasil, de abril a junho de 1995.... |
SourceID | crossref |
SourceType | Aggregation Database |
StartPage | 566 |
Title | Dengue: inquérito sorológico pós-epidêmico em zona urbana do Estado de São Paulo (Brasil) |
Volume | 33 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lj9MwELa6ywUJIZ5ieckHDqAoIo0TJ-HWbbvaQwWHFsSJyrGdVaRtXBJy2b_DCa77E_LHGD_aBBYEe-CSh2WPnc7X8efx2EbohSA0pwGXfkRF4kdhkvtMpGOfFlnKKRFZxrUr-3SZvP2YzubRfDTabcDcp_1XTUMa6FqvnL2GtvdCIQGeQedwBa3D9Z_0PpPVWWsWnJfV59bOg9fwt_UaVatz_X5MwNopb2ufG19uoZE632Sj0-XGuwB67rV1zuAmlDcHBgk3Ib2lyUeUCShUmp0e16zRbuRsyHL1hAOU0SUaZqqZwKOtcPJTeNCi3Bj2-qGsz4zs2XnJvIU3tceWW2iV8EGl3tjUOBHa8sJb9U7cqT5ehHkn-z5U9TGQC-lO_3snWFm7IGbh1vxlg3ARZ7ZJ5KeZi3-Vv0lzptzuqeEgO7TLMaWDLj62BwNd6T3iLLDz1060bovZsUYzpb7D3AUJ_NKP7qMb9bgKRK2NoPUVQQfoRghWcT_-d94BEhJLG1zlLhgRBL3-Q4sGVGrAiVZ30G03mMETi8K7aCSre-iW9QRju8DtPvpkEfkGazx23zQWscFid6lxiLfdpcVg913jD8sN1vjDFn9YKGzxh4XEy-6rwgZ7-KVF3qsH6P3JfDU99d2pHj4Hdqk3r6UBySjQygK-I-YFcNqchcD8E85IIoFQc5mFBQ3ytIDhbprwADKkCWEh4TwiD9FhpSr5COEkzNmYZgUNcxpRNs7B1IiQ54XIeTzm7AgFux9ovbWbt6z_opzH1y_yBN3sQfsUHX6pW_kMHTSifW40_AMS9oRw |
link.rule.ids | 315,782,786,866,27933,27934 |
linkProvider | Directory of Open Access Journals |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Dengue%3A+inqu%C3%A9rito+sorol%C3%B3gico+p%C3%B3s-epid%C3%AAmico+em+zona+urbana+do+Estado+de+S%C3%A3o+Paulo+%28Brasil%29&rft.jtitle=Revista+de+sa%C3%BAde+p%C3%BAblica&rft.au=Lima%2C+Virg%C3%ADlia+L+C+de&rft.au=Figueiredo%2C+Luiz+T+M&rft.au=Correa+F%2C+Heleno+R&rft.au=Leite%2C+Odair+F&rft.date=1999-12-01&rft.issn=0034-8910&rft.eissn=0034-8910&rft.volume=33&rft.issue=6&rft.spage=566&rft.epage=574&rft_id=info:doi/10.1590%2FS0034-89101999000600008&rft.externalDBID=n%2Fa&rft.externalDocID=10_1590_S0034_89101999000600008 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0034-8910&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0034-8910&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0034-8910&client=summon |