Crohn's disease
Crohn's disease is a chronic inflammatory bowel disease of unknown aetiology associated with an impaired immune response, with periods of activity and remission. It is characterized by patchy and transmural lesions which can affect the entire gastrointestinal tract, from the mouth to the anus....
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Published in: | Medicina clínica (English ed.) Vol. 151; no. 1; pp. 26 - 33 |
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Main Authors: | , , |
Format: | Journal Article |
Language: | English |
Published: |
Elsevier España, S.L.U
13-07-2018
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Subjects: | |
Online Access: | Get full text |
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Summary: | Crohn's disease is a chronic inflammatory bowel disease of unknown aetiology associated with an impaired immune response, with periods of activity and remission. It is characterized by patchy and transmural lesions which can affect the entire gastrointestinal tract, from the mouth to the anus. The most frequent symptoms are abdominal pain and diarrhoea, which can seriously affect patients’ quality of life. The increasing incidence and prevalence of the disease in our area has had a large impact on clinical practice, with the rapid development of diagnostic and therapeutic techniques. To reduce the risk of complications, primary care physicians and gastroenterologists should be familiar with the management of the disease.
La enfermedad de Crohn es una enfermedad inflamatoria intestinal crónica de etiología desconocida asociada a una respuesta inmunológica alterada que cursa con períodos de actividad y remisión. Puede afectar a cualquier tramo del tracto gastrointestinal, desde la boca hasta el ano, principalmente de forma transmural y parcheada. Los síntomas más frecuentes son el dolor abdominal y la diarrea, pudiendo afectar gravemente la calidad de vida de los pacientes. El aumento de su incidencia y prevalencia en nuestro medio ha condicionado un creciente impacto en la práctica clínica habitual así como un rápido desarrollo de técnicas diagnósticas y terapéuticas. Es por ello que tanto médicos de familia como especialistas deben estar familiarizados con el manejo de la enfermedad. |
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ISSN: | 2387-0206 2387-0206 |
DOI: | 10.1016/j.medcle.2018.05.006 |