Efectividad de un programa de instilación de quimioterapia precoz en pacientes con cáncer de vejiga

Resumen Objetivo Determinar la efectividad de un programa de tratamiento con quimioterapia precoz para pacientes con cáncer vesical no músculo infiltrante antes y después de un plan de formación y comunicación dirigido a los profesionales que intervienen en el mismo. Método Estudio longitudinal pros...

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Published in:	Revista de calidad asistencial Vol. 31; no. 4; pp. 234 - 238
Main Authors:	Beardo Villar, P, Pérez Pérez, A.B, Castro Dorantes, M.J, Jiménez Delgado, S.J, Alamillos Ortega, P, Gavira Moreno, R
Format:	Journal Article
Language:	Spanish
Published:	Elsevier España, S.L.U 01-07-2016
Subjects:	Adherencia al tratamiento Cáncer vesical no músculo infiltrante Early single instillation mitomycin C Internal Medicine Mitomicina C intravesical precoz Non-muscle invasive bladder cancer Treatment adherence Non-muscle invasive bladder cancer Treatment adherence Adherencia al tratamiento Early single instillation mitomycin C Mitomicina C intravesical precoz Cáncer vesical no músculo infiltrante
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Abstract	Resumen Objetivo Determinar la efectividad de un programa de tratamiento con quimioterapia precoz para pacientes con cáncer vesical no músculo infiltrante antes y después de un plan de formación y comunicación dirigido a los profesionales que intervienen en el mismo. Método Estudio longitudinal prospectivo, no experimental, de una cohorte de 349 pacientes con diagnóstico endoscópico de tumor vesical no músculo infiltrante en el AGS norte de Cádiz, entre 2010 y 2013, subsidiarios de tratamiento con mitomicina C posoperatoria. Resultados La tasa media de pacientes incluidos en el programa fue del 53,9%. Esta tasa aumentó un 79,3% a los 3 años. La reducción absoluta del riesgo de recidiva para los pacientes que recibieron QTp fue del 18,1% (IC 95%: 8,8-27,4, p < 0,001), y el número de pacientes necesario a tratar de 5,5 (IC 95%: 3,6-11,3, p < 0,001). Conclusiones Un programa de quimioterapia precoz postoperatoria que contemple un plan de evaluación y difusión de resultados ha conseguido un adecuado nivel de adherencia entre los profesionales, obteniendo el impacto esperado en la disminución de la recidiva precoz del cáncer de vejiga no músculo infiltrante.
AbstractList	Determinar la efectividad de un programa de tratamiento con quimioterapia precoz para pacientes con cáncer vesical no músculo infiltrante antes y después de un plan de formación y comunicación dirigido a los profesionales que intervienen en el mismo. Estudio longitudinal prospectivo, no experimental, de una cohorte de 349 pacientes con diagnóstico endoscópico de tumor vesical no músculo infiltrante en el AGS norte de Cádiz, entre 2010 y 2013, subsidiarios de tratamiento con mitomicina C posoperatoria. La tasa media de pacientes incluidos en el programa fue del 53,9%. Esta tasa aumentó un 79,3% a los 3 años. La reducción absoluta del riesgo de recidiva para los pacientes que recibieron QTp fue del 18,1% (IC 95%: 8,8-27,4, p<0,001), y el número de pacientes necesario a tratar de 5,5 (IC 95%: 3,6-11,3, p<0,001). Un programa de quimioterapia precoz postoperatoria que contemple un plan de evaluación y difusión de resultados ha conseguido un adecuado nivel de adherencia entre los profesionales, obteniendo el impacto esperado en la disminución de la recidiva precoz del cáncer de vejiga no músculo infiltrante. To determine the effectiveness of early intravesical chemotherapy intervention for patients with non-muscle invasive bladder cancer, before and after a training and inter-professional communication plan. Non-experimental prospective longitudinal study of a cohort of 349 patients with endoscopic diagnosis of a non-muscle invasive bladder tumour in Northern Area Health Management of Cadiz between 2010 and 2013 and amenable to postoperative treatment with mitomycin C. The mean rate of patients included in the program was 53.9%. The inclusion rate rose by 79.3% at 3 years. The absolute risk reduction of recurrence for patients receiving treatment is 18.1% (95% CI; 8.81% - 27.48%, p<.001), and the number of patients needed to treat was 5.5 (95% CI; 3.6 - 11.3, p<.001). A program of early postoperative chemotherapy that includes a plan for evaluation and dissemination of results has achieved a good level of adherence among professionals, obtaining the expected impact on the reduction of early recurrence of non-muscle invasive bladder cancer. Resumen Objetivo Determinar la efectividad de un programa de tratamiento con quimioterapia precoz para pacientes con cáncer vesical no músculo infiltrante antes y después de un plan de formación y comunicación dirigido a los profesionales que intervienen en el mismo. Método Estudio longitudinal prospectivo, no experimental, de una cohorte de 349 pacientes con diagnóstico endoscópico de tumor vesical no músculo infiltrante en el AGS norte de Cádiz, entre 2010 y 2013, subsidiarios de tratamiento con mitomicina C posoperatoria. Resultados La tasa media de pacientes incluidos en el programa fue del 53,9%. Esta tasa aumentó un 79,3% a los 3 años. La reducción absoluta del riesgo de recidiva para los pacientes que recibieron QTp fue del 18,1% (IC 95%: 8,8-27,4, p < 0,001), y el número de pacientes necesario a tratar de 5,5 (IC 95%: 3,6-11,3, p < 0,001). Conclusiones Un programa de quimioterapia precoz postoperatoria que contemple un plan de evaluación y difusión de resultados ha conseguido un adecuado nivel de adherencia entre los profesionales, obteniendo el impacto esperado en la disminución de la recidiva precoz del cáncer de vejiga no músculo infiltrante.
Author	Castro Dorantes, M.J Jiménez Delgado, S.J Alamillos Ortega, P Beardo Villar, P Pérez Pérez, A.B Gavira Moreno, R
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Keywords	Non-muscle invasive bladder cancer Treatment adherence Adherencia al tratamiento Early single instillation mitomycin C Mitomicina C intravesical precoz Cáncer vesical no músculo infiltrante
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Snippet	Resumen Objetivo Determinar la efectividad de un programa de tratamiento con quimioterapia precoz para pacientes con cáncer vesical no músculo infiltrante... Determinar la efectividad de un programa de tratamiento con quimioterapia precoz para pacientes con cáncer vesical no músculo infiltrante antes y después de un...
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SubjectTerms	Adherencia al tratamiento Cáncer vesical no músculo infiltrante Early single instillation mitomycin C Internal Medicine Mitomicina C intravesical precoz Non-muscle invasive bladder cancer Treatment adherence
Title	Efectividad de un programa de instilación de quimioterapia precoz en pacientes con cáncer de vejiga
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