Synthesis of new η6-(arene) chromium tricarbonyl complexes of isoxazolidines by 1,3-dipolar cycloaddition

• Published in: Russian chemical bulletin Vol. 61; no. 11; pp. 2076 - 2081
• Main Authors: Artemov, A. N., Sazonova, E. V., Mavrina, E. A., Zarovkina, N. Yu
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01-11-2012
• Subjects: Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Full Article; Inorganic Chemistry; Organic Chemistry; isoxazolidine; (arene) chromium tricarbonyl; η; nitrone; 1,3-dipolar cycloaddition
• ISSN: 1066-5285; 1573-9171
• DOI: 10.1007/s11172-012-0290-4

The 1,3-dipolar cycloaddition products of
C,N
-disubstituted nitrones and different
in situ
prepared mono-
N
-substituted nitrones to η
6
-(styrene) chromium tricarbonyl and η
6
-(ethyl cynnamate) chromium tricarbonyl were synthesized and characterized by HPLC, IR,
1
H NMR spectroscopy, and mass spectrometry. The resulted isoxazolidines were produced with a full regioselectivity and high stereoselectivity reached 100% in most cases.