Front Cover: Electrochemical Selenation/Cyclization of Quinones: A Rapid, Green and Efficient Access to Functionalized Trypanocidal and Antitumor Compounds (Eur. J. Org. Chem. 29/2020)

• Published in: European journal of organic chemistry Vol. 2020; no. 29; p. 4433
• Main Authors: Kharma, Ammar, Jacob, Claus, Bozzi, Ícaro A. O., Jardim, Guilherme A. M., Braga, Antonio L., Salomão, Kelly, Gatto, Claudia C., Silva, Maria Francilene S., Pessoa, Claudia, Stangier, Maximilian, Ackermann, Lutz, da Silva Júnior, Eufrânio N.
• Format: Journal Article
• Language: English
• Published: 09-08-2020
• ISSN: 1434-193X; 1099-0690
• DOI: 10.1002/ejoc.202001035

The Front Cover shows the power of electricity to mediate selenation reactions. In our image a Tesla static electricity generator, in honor of Nikola Tesla, was used to generate the electricity that enables the reaction between diphenyl diselenide and lapachol to prepare selenium‐containing lapachones. The rapid, green and efficient protocol avoids chemical oxidants and allows the synthesis of target molecules in a fast and reliable way. Our paper also describes compounds with activity against five cancer cell lines and Trypanosoma cruzi, the parasite that causes Chagas disease. More information can be found in the Full Paper by C. Jacob, L. Ackermann, E. N. da Silva Júnior et al.