Targeting Diabetic Cardiomyopathy: LncRNA Kcnq1ot1 Rescues Mitochondrial ATP Synthase via Sponging of MiR‐378a‐5p

Diabetes mellitus has been linked to an increase in mitochondrial microRNA‐378a (miR‐378a) content. Twenty‐five‐week‐old miR‐378a knockout Db/Db mice display preserved mt‐ATP6 and ATP synthase protein content, ATP synthase activity, and preserved cardiac function, supporting the hypothesis that miR‐...

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Bibliographic Details

Published in:	The FASEB journal Vol. 36; no. S1
Main Authors:	Durr, Andrya J., Hathaway, Quincy A., Kunovac, Amina, Taylor, Andrew D., Rizwan, Saira, Cook, Chris C., Hollander, John M.
Format:	Journal Article
Language:	English
Published:	United States The Federation of American Societies for Experimental Biology 01-05-2022
Online Access:	Get full text
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