Generation of the aspirin-exacerbated respiratory disease (AERD) phenotype by Th1/Th2 cytokines

[...]IL-4, but not IL-13 or IFN-γ, significantly inhibited monocyte and eosinophil cox-2 mRNA expression while having no influence on cox-1.

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Published in:Journal of allergy and clinical immunology Vol. 115; no. 2; p. S116
Main Authors: Borish, L., Hise, K., Negri, J., Caughey, R., Steinke, J.W.
Format: Journal Article
Language:English
Published: St. Louis Mosby, Inc 01-02-2005
Elsevier Limited
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Abstract [...]IL-4, but not IL-13 or IFN-γ, significantly inhibited monocyte and eosinophil cox-2 mRNA expression while having no influence on cox-1.
AbstractList [...]IL-4, but not IL-13 or IFN-γ, significantly inhibited monocyte and eosinophil cox-2 mRNA expression while having no influence on cox-1.
Author Caughey, R.
Negri, J.
Steinke, J.W.
Borish, L.
Hise, K.
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  organization: Otolaryngology, University Of Virginia Health Systems, Charlottesville, VA
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  surname: Steinke
  fullname: Steinke, J.W.
  organization: Beirne Carter Center for Immunology Research, University Of Virginia Health Systems, Charlottesville, VA
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Snippet [...]IL-4, but not IL-13 or IFN-γ, significantly inhibited monocyte and eosinophil cox-2 mRNA expression while having no influence on cox-1.
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SubjectTerms Cytokines
Gene expression
Genotype & phenotype
Title Generation of the aspirin-exacerbated respiratory disease (AERD) phenotype by Th1/Th2 cytokines
URI https://dx.doi.org/10.1016/j.jaci.2004.12.478
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Volume 115
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