Hemipelvectomy for the treatment of high-grade sarcomas: Pronostic of chondrosarcomas compared to other histological types

• Published in: Revista española de cirugía ortopédica y traumatología Vol. 60; no. 1; pp. 67 - 74
• Main Authors: Arnal-Burró, J, Calvo-Haro, J A, Igualada-Blazquez, C, Gil-Martínez, P, Cuervo-Dehesa, M, Vaquero-Martín, J
• Format: Journal Article
• Language: English; Spanish
• Published: Spain 01-01-2016
• Subjects: Adolescent; Adult; Aged; Bone Neoplasms - mortality; Bone Neoplasms - pathology; Bone Neoplasms - surgery; Case-Control Studies; Chondrosarcoma - mortality; Chondrosarcoma - pathology; Chondrosarcoma - surgery; Female; Follow-Up Studies; Hemipelvectomy; Humans; Male; Middle Aged; Neoplasm Grading; Pelvic Bones - pathology; Pelvic Bones - surgery; Prognosis; Prospective Studies; Recovery of Function; Sarcoma - mortality; Sarcoma - pathology; Sarcoma - surgery; Survival Analysis; Treatment Outcome; Young Adult; Sarcoma pélvico; Condrosarcoma pélvico; Hemipelvectomy; High grade sarcomas; Pelvic chondrosarcoma; Hemipelvectomía; Pelvic sarcoma; Survival; Sarcoma alto grado; Supervivencia
• ISSN: 1988-8856; 1988-8856
• DOI: 10.1016/j.recote.2015.11.003

The low incidence and histological heterogeneity of primary sarcomas located in the pelvis makes it difficult to find homogeneous cohorts.
To describe the life and functional prognosis depending on the histological type of sarcoma in a series of locally advanced high-grade pelvis located sarcomas treated by hemipelvectomy.
A descriptive epidemiological and functional study was conducted on 15 cases treated between 2006 and 2012. Survival analysis, functional assessment, and a comparative study by histological type were performed, comparing chondrosarcomas to other histological diagnoses.
The most frequent histological type was chondrosarcoma (46%), and the most frequent location was P2 (periacetabular) (73%). An internal hemipelvectomy was performed in 66% of cases, with a higher incidence (83%) in chondrosarcomas. Overall two-year survival was 54%, with higher survival in the chondrosarcoma group (67%) than in the other sarcomas (43%). Functional status depended on the type of intervention, with no differences in histological type or the performance of the reconstruction.
Hemipelvectomy is a surgical procedure that is indicated for the treatment of locally advanced high grade pelvis located sarcomas, regardless of histological type. The incidence of limb preservation and overall survival is higher in chondrosarcomas compared to other sarcomas.