Novel Assay for the Identification of NOTCH1 PEST Domain Mutations Using Fragment Analysis and Allele Specific PCR

Abstract 5127 NOTCH1 is a proto-oncogene with activating mutations described in a variety of malignancies, including acute lymphoblastic leukemia (ALL), mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL). While the prognostic significance of NOTCH1 mutations remains controversial in A...

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Bibliographic Details

Published in:	Blood Vol. 120; no. 21; p. 5127
Main Authors:	Campregher, Paulo Vidal, Petroni, Roberta Cardoso, Muto, Nair, Santana, Rubia, Sitnik, Roberta, Ramos, Oziris P S, Bacal, Nydia, Bub, Carolina B, Santos, Fabio P S, Guilherme, Perini, Ricardo, Helman, Souza, Clarissa, de Assis, Reijane Alves, Oliveira, Gislaine Borba, Metze, Irene L, Hamerschlak, Nelson
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 16-11-2012
Online Access:	Get full text
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