Outpatient treatment of Graves disease patients with fixed I 131activity

• Published in: Klinicheskai͡a︡ i ėksperimentalʹnai͡a︡ tireoidologii͡a Vol. 9; no. 1; pp. 38 - 41
• Main Authors: Isheyskaya, M S, Sleptsov, I V, Semenov, A A, Chernikov, R A, Chinchuk, I K, Uspenskaya, A A, Makaryin, V A, Fedotov, Yu N, Pashko, A A, Bubnov, A N
• Format: Journal Article
• Language: English; Russian
• Published: Endocrinology Research Centre 15-03-2013
• Subjects: graves disease; radioiodine treatment; thyrotoxicosis
• ISSN: 1995-5472; 2310-3787
• DOI: 10.14341/ket20139138-41

Results of treatment of 32 Graves disease patients with fixed activity of I131 in an outpatient mode were analyzed. 131 acitivty was 15 mCi (555 MBq). Mean age of patients was 48.5 years (20–70 years). Mean thyroid volume – 23 ± 13.9 ml. In 5 (15.6%) patients relapse of thyrotoxicosis was observed. Stable euthyroid state was revealed in 1 (3.1%) patient (follow up period 18 months). In 26 (81.3%) patients hypothyroidism occurred after the treatment. Total effectiveness of the treatment was 84.4%. In a group of patients with thyroid volume less than 50 ml total effec tiveness of the treatment was 93.1%.