Discrepancies in p21ras, p53, and Mdm2 Protein Expression Predict Worse Prognosis in Acute Myeloid Leukemia

Tumor progress is a multistep process in which clones of cells become abnormal by accumulating growth alterations until they are transformed and/or immortalized. In order to verify a potential role for p53, mdm2, and Ras genes in acute leukemogenesis, we investigated the expression and mutational st...

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Bibliographic Details
Published in:Blood Vol. 106; no. 11; p. 4521
Main Authors: Schulz, Elizabeth, Lorand-Metze, Irene, Koch, Rainer, Costa, Solange Campelo, Costa, Fernando Ferreira, Saad, Sara Terezinha Olalla
Format: Journal Article
Language:English
Published: Elsevier Inc 16-11-2005
Online Access:Get full text
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