Tumor de células gigantes ósseo: aspectos clínicos e radiográficos de 115 casos
OBJETIVO: Analisar os aspectos clínicos e radiográficos em pacientes com diagnóstico de tumor de células gigantes ósseo, confirmado por histopatologia. MATERIAIS E MÉTODOS: Os dados clínicos e radiológicos (quando disponíveis) de 115 pacientes com diagnóstico de tumor de células gigantes ósseo foram...
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Published in: | Radiologia brasileira Vol. 39; no. 2; pp. 119 - 122 |
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01-04-2006
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Abstract | OBJETIVO: Analisar os aspectos clínicos e radiográficos em pacientes com diagnóstico de tumor de células gigantes ósseo, confirmado por histopatologia. MATERIAIS E MÉTODOS: Os dados clínicos e radiológicos (quando disponíveis) de 115 pacientes com diagnóstico de tumor de células gigantes ósseo foram analisados no presente estudo. RESULTADOS: Dos casos avaliados, 57,4% (66) eram do sexo feminino e 80% (92) eram da raça branca. A média de idade dos pacientes foi de 30 anos e a topografia mais freqüente das lesões foi a metáfise distal do fêmur, em 22,6% (26) dos casos. O aspecto radiográfico mais comum foi o de lesão puramente lítica, em 63,7% (51) dos casos. CONCLUSÃO: O tumor de células gigantes é uma neoplasia óssea relativamente comum, com predomínio em indivíduos da raça branca e com aspecto radiológico bem definido.
OBJECTIVE: To review clinical and radiographic findings in patients with histologically confirmed giant cell tumor of bone. MATERIALS AND METHODS: Clinical and radiological data of 115 patients with giant cell tumor of bone were analyzed. RESULTS: Of the evaluated cases, 57.4% (66) were female and 80% (92) were white. The patients were 30 years old in average and the most common site of the lesions was the distal femoral metaphysis, in 22.6% (26). The most common radiographic aspect was a purely lytic lesion, in 63.7% (51) of the cases. CONCLUSION: Giant cell tumor of bone is not an uncommon tumor, predominant in the white race, with radiological findings well established. |
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AbstractList | OBJETIVO: Analisar os aspectos clínicos e radiográficos em pacientes com diagnóstico de tumor de células gigantes ósseo, confirmado por histopatologia. MATERIAIS E MÉTODOS: Os dados clínicos e radiológicos (quando disponíveis) de 115 pacientes com diagnóstico de tumor de células gigantes ósseo foram analisados no presente estudo. RESULTADOS: Dos casos avaliados, 57,4% (66) eram do sexo feminino e 80% (92) eram da raça branca. A média de idade dos pacientes foi de 30 anos e a topografia mais freqüente das lesões foi a metáfise distal do fêmur, em 22,6% (26) dos casos. O aspecto radiográfico mais comum foi o de lesão puramente lítica, em 63,7% (51) dos casos. CONCLUSÃO: O tumor de células gigantes é uma neoplasia óssea relativamente comum, com predomínio em indivíduos da raça branca e com aspecto radiológico bem definido.
OBJECTIVE: To review clinical and radiographic findings in patients with histologically confirmed giant cell tumor of bone. MATERIALS AND METHODS: Clinical and radiological data of 115 patients with giant cell tumor of bone were analyzed. RESULTS: Of the evaluated cases, 57.4% (66) were female and 80% (92) were white. The patients were 30 years old in average and the most common site of the lesions was the distal femoral metaphysis, in 22.6% (26). The most common radiographic aspect was a purely lytic lesion, in 63.7% (51) of the cases. CONCLUSION: Giant cell tumor of bone is not an uncommon tumor, predominant in the white race, with radiological findings well established. |
Author | Fonte, Alexandre Calábria da Lusa, Joel Rodrigo Beal Gonçalves, Carlos Marcelo Catalan, Julian Oliveira, Alex Dias de Lima, Ana Carolina Mori Melo, Elisa Soares de Justino Júnior, Reinaldo Ottero Min, Tjioe Tjia |
Author_xml | – sequence: 1 givenname: Julian surname: Catalan fullname: Catalan, Julian organization: Hospital do Câncer- A.C. Camargo – sequence: 2 givenname: Alexandre Calábria da surname: Fonte fullname: Fonte, Alexandre Calábria da organization: Hospital do Câncer- A.C. Camargo – sequence: 3 givenname: Joel Rodrigo Beal surname: Lusa fullname: Lusa, Joel Rodrigo Beal organization: Hospital do Câncer- A.C. Camargo – sequence: 4 givenname: Alex Dias de surname: Oliveira fullname: Oliveira, Alex Dias de organization: Hospital do Câncer- A.C. Camargo – sequence: 5 givenname: Elisa Soares de surname: Melo fullname: Melo, Elisa Soares de organization: Hospital do Câncer- A.C. Camargo – sequence: 6 givenname: Reinaldo Ottero surname: Justino Júnior fullname: Justino Júnior, Reinaldo Ottero organization: Hospital do Câncer- A.C. Camargo – sequence: 7 givenname: Tjioe Tjia surname: Min fullname: Min, Tjioe Tjia organization: Hospital do Câncer- A.C. Camargo – sequence: 8 givenname: Ana Carolina Mori surname: Lima fullname: Lima, Ana Carolina Mori organization: Hospital do Câncer- A.C. Camargo – sequence: 9 givenname: Carlos Marcelo surname: Gonçalves fullname: Gonçalves, Carlos Marcelo organization: Hospital do Câncer- A.C. Camargo |
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Cites_doi | 10.1172/JCI112838 10.1007/s00330-003-1902-z 10.1093/jjco/28.5.323 10.1007/s00256-003-0682-5 10.1148/radiographics.21.5.g01se251283 10.1148/rg.231015088 10.2214/ajr.166.1.8571864 |
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References_xml | – volume: 79 start-page: 483 issn: 0021-9738 year: 1987 ident: ref1 article-title: Human giant cell tumors of bone identification and characterization of cell types publication-title: J Clin Invest doi: 10.1172/JCI112838 contributor: fullname: Goldring SR – volume: 13 start-page: 1820 issn: 0938-7994 year: 2003 ident: ref9 article-title: Benign bone tumors and tumor-like lesions: value of cross-sectional imaging publication-title: Eur Radiol doi: 10.1007/s00330-003-1902-z contributor: fullname: Woertler K – volume: 28 start-page: 323 issn: 0368-2811 year: 1998 ident: ref12 article-title: Giant cell tumor of bone: oncological and functional results of long-term follow-up publication-title: Jpn J Clin Oncol doi: 10.1093/jjco/28.5.323 contributor: fullname: Oda Y – volume: 33 start-page: 169 issn: 0364-2348 year: 2004 ident: ref2 article-title: Spontaneous malignant transformation of conventional giant cell tumor publication-title: Skeletal Radiol doi: 10.1007/s00256-003-0682-5 contributor: fullname: Grote HJ – volume: 21 start-page: 1283 issn: 0271-5333 year: 2001 ident: ref6 article-title: Imaging of giant cell tumor and giant cell reparative granuloma of bone: radiologic-pathologic correlation publication-title: RadioGraphics doi: 10.1148/radiographics.21.5.g01se251283 contributor: fullname: Murphey MD – start-page: 3613 volume-title: Tumors and tumor-like lesions of bone: radiographic principles year: 1995 ident: ref8 contributor: fullname: Resnick D – volume: 23 start-page: 157 issn: 0271-5333 year: 2003 ident: ref5 article-title: Cortical lesions of the tibia: characteristic appearances at conventional radiography publication-title: RadioGraphics doi: 10.1148/rg.231015088 contributor: fullname: Levine SM – volume: 31 start-page: 411 issn: 0033-8389 year: 1993 ident: ref10 article-title: Magnetic resonance imaging of primary skeletal neoplasms publication-title: Radiol Clin North Am contributor: fullname: Berquist TH – start-page: 263 volume-title: Giant cell tumor year: 1996 ident: ref3 contributor: fullname: Unni KK – volume: 31 start-page: 299 issn: 0033-8389 year: 1993 ident: ref14 article-title: Giant cell tumors of bone publication-title: Radiol Clin North Am contributor: fullname: Manaster BJ – volume: 166 start-page: 145 issn: 0361-803X year: 1996 ident: ref11 article-title: MR findings indicative of hemosiderin in giant cell tumor of bone: frequency, cause, and diagnostic significance publication-title: AJR doi: 10.2214/ajr.166.1.8571864 contributor: fullname: Aoki J – volume: 1 start-page: 249 issn: 0390-5489 year: 1975 ident: ref7 article-title: Giant cell tumors of bone: a study of 209 cases with long-term follow-up in 130 publication-title: Ital J Orthop Traumatol contributor: fullname: Campanacci M – volume: 28 start-page: 239 issn: 0341-2695 year: 2004 ident: ref13 article-title: Giant cell tumors of bone: an analysis of 87 cases publication-title: Int Orthop contributor: fullname: Su YP – start-page: 332 year: 1980 ident: ref4 contributor: fullname: Mirra JM |
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