Autocrine regulation of human sperm motility by tachykinins

We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa. Freshly ejaculated semen was collected from forty-eight normozoospermic human donors. We analyzed the expression of substance P, neurokinin A, neur...

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Bibliographic Details
Published in:	Reproductive biology and endocrinology Vol. 8; no. 1; p. 104
Main Authors:	Pinto, Francisco M, Ravina, Cristina G, Subiran, Nerea, Cejudo-Román, Antonio, Fernández-Sánchez, Manuel, Irazusta, Jon, Garrido, Nicolas, Candenas, Luz
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 26-08-2010 BioMed Central BMC
Subjects:	Adolescent Adult Antidepressive Agents - pharmacology Antipsychotic Agents - pharmacology Autocrine Communication - drug effects Autocrine Communication - genetics Benzamides - pharmacology Drug Evaluation, Preclinical Experiments Gene expression Humans Male Messenger RNA Motility Narcotics Neprilysin - genetics Neprilysin - metabolism Neurokinin A - genetics Neurokinin A - metabolism Neurokinin B - genetics Neurokinin B - metabolism Peptides Piperidines - pharmacology Polymerase chain reaction Proteins Receptors, Tachykinin - antagonists & inhibitors Receptors, Tachykinin - genetics Receptors, Tachykinin - physiology RNA, Messenger - analysis Sperm Sperm Motility - drug effects Sperm Motility - genetics Sperm Motility - physiology Spermatozoa Spermatozoa - chemistry Spermatozoa - drug effects Spermatozoa - metabolism Studies Tachykinins Tachykinins - genetics Tachykinins - metabolism Tachykinins - physiology Young Adult
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