Regulation of chk1

Chk1 is a serine/threonine protein kinase that is the effector of the G2 DNA damage checkpoint. Chk1 homologs have a highly conserved N-terminal kinase domain, and a less conserved C-terminal regulatory domain of ~200 residues. In response to a variety of genomic lesions, a number of proteins collab...

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Bibliographic Details

Published in:	Cell division Vol. 4; no. 1; p. 8
Main Authors:	Tapia-Alveal, Claudia, Calonge, Teresa M, O'Connell, Matthew J
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 29-04-2009 BioMed Central BMC
Subjects:	Review
Online Access:	Get full text
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