CAREX Canada: an enhanced model for assessing occupational carcinogen exposure

• Published in: Occupational and environmental medicine (London, England) Vol. 72; no. 1; pp. 64 - 71
• Main Authors: Peters, Cheryl E, Ge, Calvin B, Hall, Amy L, Davies, Hugh W, Demers, Paul A
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group 01-01-2015; BMJ Publishing Group LTD
• Series: Original article
• Subjects: Canada; Cancer; Carcinogens; Carex; Censuses; Databases, Factual; Disease prevention; Estimates; European Union; Exhaust emissions; Exposure; Exposure Assessment; Humans; Industry; Models, Theoretical; Occupation; Occupational; Occupational exposure; Occupational Exposure - statistics & numerical data; Occupations; Prevalence; Priorities; Provinces; Sex Factors; Shift work; Solar radiation; Surveillance; Trends; Ultraviolet radiation; Working conditions; Workplaces; Canada; ANW, Canada
• ISSN: 1351-0711; 1470-7926
• DOI: 10.1136/oemed-2014-102286

Objectives To estimate the numbers of workers exposed to known and suspected occupational carcinogens in Canada, building on the methods of CARcinogen EXposure (CAREX) projects in the European Union (EU). Methods CAREX Canada consists of estimates of the prevalence and level of exposure to occupational carcinogens. CAREX Canada includes occupational agents evaluated by the International Agency for Research on Cancer as known, probable or possible human carcinogens that were present and feasible to assess in Canadian workplaces. A Canadian Workplace Exposure Database was established to identify the potential for exposure in particular industries and occupations, and to create exposure level estimates among priority agents, where possible. CAREX EU data were reviewed for relevance to the Canadian context and the proportion of workers likely to be exposed by industry and occupation in Canada was assigned using expert assessment and agreement by a minimum of two occupational hygienists. These proportions were used to generate prevalence estimates by linkage with the Census of Population for 2006, and these estimates are available by industry, occupation, sex and province. Results CAREX Canada estimated the number of workers exposed to 44 known, probable and suspected carcinogens. Estimates of levels of exposure were further developed for 18 priority agents. Common exposures included night shift work (1.9 million exposed), solar ultraviolet radiation exposure (1.5 million exposed) and diesel engine exhaust (781 000 exposed). Conclusions A substantial proportion of Canadian workers are exposed to known and suspected carcinogens at work.