Analysis of lapine cartilage matrix after radiosynovectomy with holmium-166 ferric hydroxide macroaggregate

Objective: To study the short and long term effects of radiosynovectomy on articular cartilage in growing and mature rabbits. Methods: The articular cartilage of the distal femurs of rabbits was examined four days, two months, and one year after radiosynovectomy with holmium-166 ferric hydroxide mac...

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Bibliographic Details
Published in:	Annals of the rheumatic diseases Vol. 62; no. 1; pp. 43 - 49
Main Authors:	Mäkelä, O T, Lammi, M J, Uusitalo, H, Hyttinen, M M, Vuorio, E, Helminen, H J, Tulamo, R-M
Format:	Journal Article
Language:	English
Published:	London BMJ Publishing Group Ltd and European League Against Rheumatism 01-01-2003 BMJ BMJ Publishing Group Ltd BMJ Publishing Group LTD
Subjects:	[166Ho] FHMA Age Factors Aggrecans Analysis Animals Arthritis Arthritis - pathology Arthritis - radiotherapy Articular cartilage Biochemistry biokemi Biological and medical sciences Blotting, Northern - methods Cartilage cells Cartilage, Articular - growth & development Cartilage, Articular - pathology Cartilage, Articular - radiation effects Collagen Collagen Type II - genetics Diseases of the osteoarticular system. Orthopedic treatment Electrophoresis, Polyacrylamide Gel Evaluation Extended Report Extracellular Matrix Proteins Femur Ferric Compounds - therapeutic use GAGs glycosaminoglycans Glycosaminoglycans - analysis High Mobility Group Proteins - genetics Histology Holmium Holmium - therapeutic use holmium-166 holmium-166 ferric hydroxide macroaggregate intramuscularly Knee Lectins, C-Type Medical sciences MEM minimum essential medium Models, Animal Molecular Biology molekylärbiologi Osteochondrosis Physiological aspects proteoglycans Proteoglycans - analysis Proteoglycans - genetics Rabbits Radioisotopes Radioisotopes - therapeutic use radiosynovectomy Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) reumatologi rheumatology RNA, Messenger - analysis SDS sodium dodecyl sulphate SOX9 Transcription Factor Statistics Statistics, Nonparametric Studies Synovial Membrane - pathology Synovial Membrane - radiation effects Transcription Factors - genetics Finland Short term Knee Animal model Femur Hindlimb Biochemical analysis Treatment efficiency Rabbit Histology Lagomorpha Experimental study Radiotherapy Long term Young animal Vertebrata Mammalia Treatment Articular cartilage Adult animal Technique Molecular biology Synovectomy
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