Chromosome studies of males in an institution for the mentally handicapped

Karyotypes were examined in 512 (91.9%) of 557 male patients in an institution for the mentally handicapped. A total of 110 (21.5%) had an abnormal karyotype: 65 (12.7%) with Down's syndrome, 30 (5.9%) with the fragile X syndrome, 13 (2.5%) with autosomal anomalies other than Down's syndro...

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Bibliographic Details
Published in:	Journal of medical genetics Vol. 26; no. 6; pp. 379 - 381
Main Authors:	English, C J, Davison, E V, Bhate, M S, Barrett, L
Format:	Journal Article
Language:	English
Published:	London BMJ Publishing Group Ltd 01-06-1989 BMJ BMJ Publishing Group LTD
Subjects:	Aneuploidy Biological and medical sciences Chromosome Aberrations Chromosome Disorders Down Syndrome - genetics Humans Intellectual Disability - genetics Karyotyping Male Medical genetics Medical sciences Mental and behavioral disorders Translocation, Genetic
Online Access:	Get full text
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Summary:	Karyotypes were examined in 512 (91.9%) of 557 male patients in an institution for the mentally handicapped. A total of 110 (21.5%) had an abnormal karyotype: 65 (12.7%) with Down's syndrome, 30 (5.9%) with the fragile X syndrome, 13 (2.5%) with autosomal anomalies other than Down's syndrome (12 unbalanced, one balanced), and two (0.4%) with sex chromosome anomalies.
Bibliography:	ark:/67375/NVC-DD3CT7Z0-F local:jmedgenet;26/6/379 istex:3370F6EC154B8A49D4273908A4E2EC698FB06126 PMID:2525623 href:jmedgenet-26-379.pdf ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2
ISSN:	0022-2593 1468-6244 1468-6244
DOI:	10.1136/jmg.26.6.379