Risperidone implicated in the onset of tardive dyskinesia in a young woman

• Published in: Postgraduate medical journal Vol. 76; no. 895; pp. 316 - 317
• Main Authors: Kumar, Shailesh, Malone, Darren M
• Format: Journal Article
• Language: English
• Published: London The Fellowship of Postgraduate Medicine 01-05-2000; BMJ; Oxford University Press; BMJ Group
• Subjects: Adolescent; Adverse Drug Reaction of the Month; Antipsychotic Agents - adverse effects; atypical antipsychotics; Biological and medical sciences; Drug toxicity and drugs side effects treatment; Dyskinesia, Drug-Induced - etiology; Female; Hallucinations; Humans; Hypotheses; Medical sciences; Pharmacology. Drug treatments; Psychosis; Psychotropic drugs; risperidone; Risperidone - adverse effects; Schizophrenia; Schizophrenia - drug therapy; tardive dyskinesia; Toxicity: nervous system and muscle; Women; Human; Nervous system diseases; Late; Neuroleptic; Psychotropic; Serotonin antagonist; Schizophrenia; Involuntary movement; Psychosis; Case study; Chemotherapy; Treatment; Buccofacial dyskinesia; Neurological disorder; Risperidone; Extrapyramidal syndrome
• ISSN: 0032-5473; 1469-0756
• DOI: 10.1136/pmj.76.895.316

The aim of this case report is to highlight that risperidone may cause and ameliorate tardive dyskinesia. A 16 year old white women with a 12 month history of schizophrenia, developed buccolingual masticatory tardive dyskinesia after receiving risperidone 6 mg. She had received small dosages of typical antipsychotics before and during receiving risperidone for short periods. Recommencement of risperidone with 2 mg and increasing to 6 mg resulted in improvement in tardive dyskinesia and up until now she remains free of any abnormal involuntary movements.