Calcium deposition in osteoarthritic meniscus and meniscal cell culture

Calcium crystals exist in the knee joint fluid of up to 65% of osteoarthritis (OA) patients and the presence of these calcium crystals correlates with the radiographic evidence of hyaline cartilaginous degeneration. This study sought to examine calcium deposition in OA meniscus and to investigate OA...

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Bibliographic Details
Published in:	Arthritis research & therapy Vol. 12; no. 2; p. R56
Main Authors:	Sun, Yubo, Mauerhan, David R, Honeycutt, Patrick R, Kneisl, Jeffrey S, Norton, H James, Zinchenko, Natalia, Hanley, Jr, Edward N, Gruber, Helen E
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 01-01-2010 BioMed Central
Subjects:	Adenosine Triphosphate - pharmacology Adult Aged Anthraquinones - chemistry Biological assay Calcium - analysis Calcium - metabolism Calcium, Dietary Care and treatment Cells, Cultured Child Chondrocalcinosis - metabolism Chondrocalcinosis - pathology Chondrocytes - drug effects Chondrocytes - metabolism Chondrocytes - pathology Development and progression Female Gene Expression Health aspects Humans Knee Joint - metabolism Knee Joint - pathology Male Medical examination Menisci, Tibial - metabolism Menisci, Tibial - pathology Meniscus (Anatomy) Methods Middle Aged Oligonucleotide Array Sequence Analysis Osteoarthritis Osteoarthritis, Knee - metabolism Osteoarthritis, Knee - pathology Phosphate Transport Proteins - genetics Phosphate Transport Proteins - metabolism Phosphoric Diester Hydrolases - genetics Phosphoric Diester Hydrolases - metabolism Physiological aspects Pyrophosphatases - genetics Pyrophosphatases - metabolism Research article Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Up-Regulation United States
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