Methotrexate in the Treatment of Psoriasis and Rheumatoid Arthritis: Mechanistic Insights, Current Issues and Novel Delivery Approaches

Our review is focused on the use of methotrexate in drug therapy of two autoimmune diseases, psoriasis and rheumatoid arthritis (RA). The article describes the pathogenesis of psoriasis and RA, the role of methotrexate in the treatment of these diseases with more focused review on the mechanism behi...

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Bibliographic Details
Published in:	Current pharmaceutical design Vol. 23; no. 24; p. 3550
Main Authors:	Rajitha, Panonnummal, Biswas, Raja, Sabitha, Mangalathillam, Jayakumar, R
Format:	Journal Article
Language:	English
Published:	Netherlands 01-01-2017
Subjects:	Animals Antirheumatic Agents - administration & dosage Arthritis, Rheumatoid - drug therapy Arthritis, Rheumatoid - metabolism Arthritis, Rheumatoid - pathology Drug Delivery Systems - methods Drug Delivery Systems - trends Humans Methotrexate - administration & dosage Methotrexate - metabolism Psoriasis - drug therapy Psoriasis - metabolism Psoriasis - pathology hydrogel psoriasis colloidal carriers immune modulatory activities Methotrexate niosomal gel rheumatoid arthritis
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