Pulmonary tuberculosis: Management in children has special considerations

Younger infants have a greatly increased risk of progression from latent infection to disease, possibly as high as 40% (compared with a 10% life-time risk in adults), with a much higher incidence of extrapulmonary tuberculosis, including tuberculous meningitis. 4 Most paediatric tuberculosis in deve...

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Bibliographic Details
Published in:	BMJ Vol. 332; no. 7554; pp. 1392 - 1393
Main Authors:	Burgner, David, Cherian, Sarah, Geddes, Janet, Shingadia, Delane
Format:	Journal Article
Language:	English
Published:	England BMJ Publishing Group LTD 10-06-2006 BMJ Publishing Group Ltd
Subjects:	Adolescent Child Child, Preschool Contact Tracing Emigration and Immigration Humans Immunology Industrialized nations Infant Infant, Newborn Infections Letters Mycobacterium Tuberculosis Tuberculosis, Pulmonary - diagnosis Tuberculosis, Pulmonary - epidemiology
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Summary:	Younger infants have a greatly increased risk of progression from latent infection to disease, possibly as high as 40% (compared with a 10% life-time risk in adults), with a much higher incidence of extrapulmonary tuberculosis, including tuberculous meningitis. 4 Most paediatric tuberculosis in developed countries The diagnosis and prompt treatment of latent infection, particularly in immigrant and refugee children, is therefore of considerable importance.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 SourceType-Other Sources-1 content type line 63 ObjectType-Correspondence-1 ObjectType-Commentary-2 Competing interests: DB is part of a research group that has received research funding support from Oxford Immunotec.
ISSN:	0959-8138 1468-5833 1756-1833
DOI:	10.1136/bmj.332.7554.1392-b