Gentamicin serum half-life: a comparison between pregnant and non-pregnant women
The serum half-life of gentamicin following an intravenous dose was compared between 19 pregnant women (28-34 weeks of pregnancy) with premature rupture of the membranes and 17 non-pregnant women with pelvic inflammatory disease, the groups being age and weight matched. A significant reduction of ge...
Saved in:
| Published in: | Postgraduate medical journal Vol. 61; no. 721; pp. 979 - 981 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
England
The Fellowship of Postgraduate Medicine
01-11-1985
Oxford University Press BMJ Group |
| Subjects: | |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | The serum half-life of gentamicin following an intravenous dose was compared between 19 pregnant women (28-34 weeks of pregnancy) with premature rupture of the membranes and 17 non-pregnant women with pelvic inflammatory disease, the groups being age and weight matched. A significant reduction of gentamicin half-life was found in the pregnant group. |
|---|---|
| AbstractList | The serum half-life of gentamicin following an intravenous dose was compared between 19 pregnant women (28-34 weeks of pregnancy) with premature rupture of the membranes and 17 non-pregnant women with pelvic inflammatory disease, the groups being age and weight matched. A significant reduction of gentamicin half-life was found in the pregnant group. Summary The serum half-life of gentamicin following an intravenous dose was compared between 19 pregnant women (28-34 weeks of pregnancy) with premature rupture of the membranes and 17 non-pregnant women with pelvic inflammatory disease, the groups being age and weight matched. A significant reduction of gentamicin half-life was found in the pregnant group. |
| Author | Lazebnik, N. Noy, S. Lazebnik, R. Amoday, I. Hezroni, Y. Aviram, A. |
| Author_xml | – sequence: 1 givenname: N. surname: Lazebnik fullname: Lazebnik, N. – sequence: 2 givenname: S. surname: Noy fullname: Noy, S. – sequence: 3 givenname: R. surname: Lazebnik fullname: Lazebnik, R. – sequence: 4 givenname: Y. surname: Hezroni fullname: Hezroni, Y. – sequence: 5 givenname: I. surname: Amoday fullname: Amoday, I. – sequence: 6 givenname: A. surname: Aviram fullname: Aviram, A. |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/4070116$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkd1rFDEUxYNU6rb67JMwIPggzPZm8zXxoSCLVrFohSriS8hk7mxnnUnGZMbqf2_KLov64lMg53fvPYdzQo588EjIYwpLSpk8GzfDdinpUq3oUit9jywol7oEJeQRWQCwVSm4Yg_ISUpbAMoUp8fkmIMCSuWCXF2gn-zQuc4XCeM8FDe2b8u-a_FFYQsXhtHGLgVf1DjdIvpijLjx1k-F9U2R3ZSHj9swoH9I7re2T_ho_56ST69fXa_flJcfLt6uX16WNa_0VLpWOGhWyrYaAFWDSoN1XEqAChrLKWhX1U2NoNtGMomVFMwxxlstRCsbdkrOd3vHuR6wcTlGtL0ZYzfY-MsE25m_Fd_dmE34YVacVlzyvODZfkEM32dMkxm65LDvrccwJ6OkACakyuDTf8BtmKPP4QxVCiqqJYhMne0oF0NKEduDFQrmripzV5WR1OSqTK4qTzz5M8GB33eT9XKnd2nCnwfZxm8mu1LCvP-8NleMvvu6_vjFXGf--Y6v853_Hf8NqEevdw |
| CitedBy_id | crossref_primary_10_2165_11538050_000000000_00000 crossref_primary_10_1097_AOG_0b013e3181cb5c0e crossref_primary_10_2165_00003495_200161140_00006 crossref_primary_10_4061_2010_385640 crossref_primary_10_1177_107155769500200105 crossref_primary_10_1016_S0246_0335_06_44025_4 crossref_primary_10_1016_S1283_081X_06_47965_0 crossref_primary_10_1097_01_AOG_0000216197_26783_b5 crossref_primary_10_1016_j_matlet_2013_09_024 crossref_primary_10_1016_S1283_081X_19_42004_3 crossref_primary_10_1016_0002_9378_89_90431_6 |
| Cites_doi | 10.1097/00003081-198306000-00021 10.7326/0003-4819-74-2-192 10.1001/jama.1972.03190340043010 |
| ContentType | Journal Article |
| Copyright | Copyright BMJ Publishing Group LTD Nov 1985 |
| Copyright_xml | – notice: Copyright BMJ Publishing Group LTD Nov 1985 |
| DBID | BSCLL CGR CUY CVF ECM EIF NPM AAYXX CITATION 3V. 7X7 7XB 88E 88I 8AF 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR BTHHO CCPQU DWQXO FYUFA GHDGH GNUQQ HCIFZ K9. M0S M1P M2P PQEST PQQKQ PQUKI PRINS Q9U 7X8 5PM |
| DOI | 10.1136/pgmj.61.721.979 |
| DatabaseName | Istex Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef ProQuest Central (Corporate) Health Medical collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Science Database (Alumni Edition) STEM Database Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central ProQuest Central Essentials ProQuest Central BMJ Journals ProQuest One Community College ProQuest Central Korea Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student SciTech Premium Collection (Proquest) (PQ_SDU_P3) ProQuest Health & Medical Complete (Alumni) Health & Medical Collection (Alumni Edition) PML(ProQuest Medical Library) ProQuest Science Journals ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest Central Basic MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef ProQuest Central Student ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest AP Science ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest Central China ProQuest Central Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea ProQuest Medical Library (Alumni) ProQuest Science Journals (Alumni Edition) ProQuest Central Basic ProQuest Science Journals ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition BMJ Journals ProQuest One Academic ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE ProQuest Central Student CrossRef |
| Database_xml | – sequence: 1 dbid: ECM name: MEDLINE url: https://search.ebscohost.com/login.aspx?direct=true&db=cmedm&site=ehost-live sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1469-0756 |
| EndPage | 981 |
| ExternalDocumentID | 3972344121 10_1136_pgmj_61_721_979 4070116 ark_67375_NVC_P31KZCQX_T |
| Genre | Journal Article Comparative Study |
| GroupedDBID | --- .55 .GJ .VT 0R~ 123 18M 29O 2WC 39C 3V. 4.4 40O 53G 5RE 5VS 5WD 7X7 7~S 88E 88I 8AF 8FI 8FJ 8R4 8R5 AABZA AACZT AAKAS AAPXW AAQQT AARHZ AAUAY AAVAP AAWDT AAWJN AAWTL ABJNI ABKDF ABNHQ ABOCM ABPTD ABTFR ABUWG ABVAJ ABXVV ACFRR ACGFO ACGFS ACGOD ACGTL ACHTP ACMFJ ACOFX ACTZY ACUTJ ACZBC ADBBV ADCEG ADFRT ADIPN ADQBN ADVEK ADZCM AENEX AFKRA AFWFF AFYAG AGMDO AGUTN AHMBA AHNKE AHQMW AJEEA ALIPV ALMA_UNASSIGNED_HOLDINGS ANFBD ASPBG ATGXG AVWKF AZFZN AZQEC BAWUL BCRHZ BENPR BOMFT BPHCQ BTFSW BTHHO BVXVI C45 CAG CCPQU COF CS3 CXRWF DIK DU5 DWQXO E3Z EBS EJD EMOBN F5P FEDTE FYUFA GNUQQ GX1 H13 HAJ HCIFZ HMCUK HVGLF HYE HZ~ IAO IEA IHR INH INR IOF ITC J5H KOP L7B M1P M2P N9A NTWIH NXWIF O9- OAUYM OCZFY OJZSN OK1 OPAEJ OVD OWPYF P2P PQQKQ PROAC PSQYO Q2X R53 RHF RHI RMJ ROX RPM RV8 TCN TEORI TR2 UAW UKHRP UYXKK V24 VM9 VVN W8F WH7 X7M Y6R YQY ZCG ZGI ABEJV BSCLL CGR CUY CVF ECM EIF NPM AAYXX CITATION 7XB 8FK K9. PQEST PQUKI PRINS Q9U 7X8 5PM |
| ID | FETCH-LOGICAL-b489t-cf5c0d27af900e7de790ac4660080da4109c8bdbe09fd636e8653c334f955f6d3 |
| IEDL.DBID | RPM |
| ISSN | 0032-5473 |
| IngestDate | Tue Sep 17 21:07:36 EDT 2024 Fri Oct 25 05:33:02 EDT 2024 Thu Oct 10 19:34:15 EDT 2024 Fri Aug 23 02:11:04 EDT 2024 Sat Sep 28 08:36:49 EDT 2024 Wed Oct 30 09:30:52 EDT 2024 Wed Aug 21 03:33:28 EDT 2024 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 721 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-b489t-cf5c0d27af900e7de790ac4660080da4109c8bdbe09fd636e8653c334f955f6d3 |
| Notes | istex:B69158F756399FBD72E9C9FBF0A9ED9BF9F23E56 PMID:4070116 ark:/67375/NVC-P31KZCQX-T href:postgradmedj-61-979.pdf local:postgradmedj;61/721/979 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://doi.org/10.1136/pgmj.61.721.979 |
| PMID | 4070116 |
| PQID | 1770819605 |
| PQPubID | 2041054 |
| PageCount | 3 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_2418464 proquest_miscellaneous_76503567 proquest_journals_1770819605 crossref_primary_10_1136_pgmj_61_721_979 pubmed_primary_4070116 istex_primary_ark_67375_NVC_P31KZCQX_T bmj_primary_10_1136_pgmj_61_721_979 |
| PublicationCentury | 1900 |
| PublicationDate | 19851101 |
| PublicationDateYYYYMMDD | 1985-11-01 |
| PublicationDate_xml | – month: 11 year: 1985 text: 19851101 day: 1 |
| PublicationDecade | 1980 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England – name: London |
| PublicationTitle | Postgraduate medical journal |
| PublicationTitleAlternate | Postgrad Med J |
| PublicationYear | 1985 |
| Publisher | The Fellowship of Postgraduate Medicine Oxford University Press BMJ Group |
| Publisher_xml | – name: The Fellowship of Postgraduate Medicine – name: Oxford University Press – name: BMJ Group |
| References | JACKSON, G.G. (ref_2) 1977 McHENRY, M.C.; GAVAN, T.L.; GILFFORD, R.W. (ref_6) 1971; 74 CUTLER, R.E.; GYSELYNCK, A.M.; FLEET, W.P. (ref_1) 1972; 219 KORZENIOWSKI, O.M.; HOOK, E.W. (ref_3) 1979 LANDERS, D.V.; GREEN, J.R.; SWEET, R.L. (ref_4) 1983; 26 MAYER, S.E.; MELMON, K.L.; GILMAN, A.G. (ref_5) 1980 |
| References_xml | – volume: 26 start-page: 391 year: 1983 ident: ref_4 article-title: Antibiotic use during pregnancy and the postpartum period publication-title: Clinical Obstetrics and Gynecology doi: 10.1097/00003081-198306000-00021 contributor: fullname: LANDERS, D.V.; GREEN, J.R.; SWEET, R.L. – start-page: 249 year: 1979 ident: ref_3 article-title: Aminocycitols: aminoglycosides and spectinomycin. In Principles and Practice of Infectious Diseases contributor: fullname: KORZENIOWSKI, O.M.; HOOK, E.W. – volume: 74 start-page: 192 year: 1971 ident: ref_6 article-title: Gentamicin dosages for renal insufficiency; adjustments based on creatinine clearance and serum creatinine concentration publication-title: Annals of Internal Medicine doi: 10.7326/0003-4819-74-2-192 contributor: fullname: McHENRY, M.C.; GAVAN, T.L.; GILFFORD, R.W. – volume: 219 start-page: 1037 year: 1972 ident: ref_1 article-title: Correlation of serum creatinine concentration and gentamicin half-life publication-title: Journal ofthe American Medical Association doi: 10.1001/jama.1972.03190340043010 contributor: fullname: CUTLER, R.E.; GYSELYNCK, A.M.; FLEET, W.P. – year: 1977 ident: ref_2 article-title: Present states of aminoglycoside antibiotics and their safe effective use publication-title: Journal of Clinical contributor: fullname: JACKSON, G.G. – start-page: 22 year: 1980 ident: ref_5 article-title: The dynamics of drug absorption, distribution and elimination. In The Pharmacological Basis of Therapeutics contributor: fullname: MAYER, S.E.; MELMON, K.L.; GILMAN, A.G. |
| SSID | ssj0013741 |
| Score | 1.3439493 |
| Snippet | The serum half-life of gentamicin following an intravenous dose was compared between 19 pregnant women (28-34 weeks of pregnancy) with premature rupture of the... Summary The serum half-life of gentamicin following an intravenous dose was compared between 19 pregnant women (28-34 weeks of pregnancy) with premature... |
| SourceID | pubmedcentral proquest crossref pubmed istex bmj |
| SourceType | Open Access Repository Aggregation Database Index Database Publisher |
| StartPage | 979 |
| SubjectTerms | Adult Creatinine - metabolism Female Fetal Membranes, Premature Rupture - blood Gentamicins - blood Half-Life Humans Pelvic Inflammatory Disease - blood Pregnancy |
| Title | Gentamicin serum half-life: a comparison between pregnant and non-pregnant women |
| URI | http://dx.doi.org/10.1136/pgmj.61.721.979 https://api.istex.fr/ark:/67375/NVC-P31KZCQX-T/fulltext.pdf https://www.ncbi.nlm.nih.gov/pubmed/4070116 https://www.proquest.com/docview/1770819605 https://search.proquest.com/docview/76503567 https://pubmed.ncbi.nlm.nih.gov/PMC2418464 |
| Volume | 61 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3da9RAEB-8itIX8as0WuuCIr4kl3S_sr7J2VopLSdWKb4sm-xue_WSHnc98M93Nl94Igg-Jrthw-ws8xvmN78FeG0LJpWSRWzDKWSsSGPlHMOcJ3WpcBxBXehGPv4izy7yD4dBJof3vTANab8sZkk9r5J6dtVwKxdVOe55YuPp6QSjDoZNNh7BCLFhn6L3pQPJ2mvyaBD5l7TT88moGC8uq-tEZAlmPYmSahvuYToTKhEYWIrqeiM03Q1W_vk33PknffK3eHT0EB50QJK8b3_4Edxx9WO4f9qVyp_A9GNghVfhiaCbrStyZeY-ns-8e0cMKYf7B0lH1SKLpbsMtBhiakvqmzoeXjQyDU_h69Hh-eQ47q5PiAuWq9u49LxM7YE0XqWpk9ZJlZqSCRFQojUsS1WZF7ZwqfJWUOFywWlJKfOKcy8s3YEtXMztArGWKyYwthvq2IH3RgrFfIHQTGahNBvBK7SfXrQCGbpJLKjQwd5aZBrtrdHeEbzt7fvvqW8a-w_zzPJHoKBJrs--TfSUZiffJ58v9HkEe_0G6e70rXQmZUA6mKlF8HIYxnMTiiGmdjfrlZYITSkXMoKddjeHpTqfiEBubPMwHgS5N0fQTxth7s4vn_33l89hO1M5b3sd92Drdrl2L2C0sut9hPufTvYbV_8F0yAAAA |
| link.rule.ids | 230,315,729,782,786,887,27935,27936,53803,53805 |
| linkProvider | National Library of Medicine |
| linkToHtml | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3db9MwED-xTcBe-J4IDGYJhHhJ68xfMW-obBRtrYooaNqL5cT21tFkVbtK_PnY-RJFSEh7TM6RFd-d7ne6350B3pqMCilFFpvghZRmOJbWUp_zYIu5ZR7UhW7k4TcxPks_HYUxOazthalI-3k265XzolfOLitu5aLI-y1PrD8ZDXzU8WGT9rdgx_srJm2S3hYPBK0vyiNhzL8gzUSfhPD-4qK46vGk5_OenhRyF-76hCbUInxoyYqrjeC0E87517-Q598Eyj8i0vHDW_7LI3jQQFD0sRY_hju2fAL3Rk2R_SlMPgc-eRGekDfQdYEu9dzF85mzH5BGeXdzIWpIXmixtBeBUIN0aVB5Xcbdi2rAwzP4fnw0HQzj5uKFOKOpvIlzx3JsDoV2EmMrjBUS65xyHvCl0TTBMk8zk1ksneGE25QzkhNCnWTMcUP2YNtvZp8DMoZJyj0q0MTSQ-e04JK6zIM6kYSibgRv_LmrRT1aQ1UpCeEq6EnxRHk9Ka-nCN63evn_0neV3rp1evkzkNcEU-MfAzUhycn54OuZmkaw3ypWNX67UokQASP5HC-Cg07sPS6UUXRpr9crJTyoJYyLCPZqK-i2amwpArFhHp08jPLelHirqEZ6N1bw4tZfHsD94XR0qk6_jE9ewm4iU1Z3TO7D9s1ybV_B1sqsX1eO8htRihSP |
| linkToPdf | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3daxQxEB9si6UvfpeuVhtQxJf9ar42vsm1Z6X2OLFK8SVkN0l79Xa73PXAP99kv_BEEPRxN7OEzcwwv2F-mQF4pXPCheB5qL0XEpInoTCGuJwnMQkz1IE6fxv55DOfXGRHx75NzjDqqyHtF_ksquZlVM2uGm5lXRZxzxOLp2cjF3Vc2CRxrW28AVvOZxPaJ-p9AYGTdlge9q3-Oe66-qSYxfVleR2xNHK5TyS42IG7Lqnx9QgXXvLyei1Abfmz_vEn9Pk7ifKXqDS-_x__8wDudVAUvWtFHsIdUz2C7bOu2P4Ypu89r7z0T8gZ6qpEV2puw_nMmrdIoWKYYIg6sheqF-bSE2uQqjSqbqpweNE0engCX8bH56OTsBvAEOYkE7dhYWmR6EOurEgSw7XhIlEFYczjTK1Imogiy3VuEmE1w8xkjOICY2IFpZZpvAubbjOzB0hrKghz6EBhQw6tVZwJYnMH7njqi7sBvHRnL-u2xYZsUhPMpNeVZKl0upJOVwG86XXzd9HXje4GObX47klsnMrJ15Gc4vT02-jThTwPYL9Xruz8dylTzj1WcrleAAfDsvM8X05RlblZLSV34BZTxgPYbS1h2KqzpwD4mokM676l9_qKs4ymtXdnCU__-csD2J4ejeXHD5PTZ7CTioy2Fyf3YfN2sTLPYWOpVy8aX_kJEbQXDw |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Gentamicin+serum+half-life%3A+a+comparison+between+pregnant+and+non-pregnant+women&rft.jtitle=Postgraduate+medical+journal&rft.au=Lazebnik%2C+N&rft.au=Noy%2C+S&rft.au=Lazebnik%2C+R&rft.au=Hezroni%2C+Y&rft.date=1985-11-01&rft.pub=Oxford+University+Press&rft.issn=0032-5473&rft.eissn=1469-0756&rft.volume=61&rft.issue=721&rft.spage=979&rft_id=info:doi/10.1136%2Fpgmj.61.721.979&rft.externalDBID=HAS_PDF_LINK&rft.externalDocID=3972344121 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0032-5473&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0032-5473&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0032-5473&client=summon |