Gentamicin serum half-life: a comparison between pregnant and non-pregnant women

Gentamicin serum half-life: a comparison between pregnant and non-pregnant women

The serum half-life of gentamicin following an intravenous dose was compared between 19 pregnant women (28-34 weeks of pregnancy) with premature rupture of the membranes and 17 non-pregnant women with pelvic inflammatory disease, the groups being age and weight matched. A significant reduction of ge...

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Bibliographic Details
Published in:Postgraduate medical journal Vol. 61; no. 721; pp. 979 - 981
Main Authors: Lazebnik, N., Noy, S., Lazebnik, R., Hezroni, Y., Amoday, I., Aviram, A.
Format: Journal Article
Language:English
Published: England The Fellowship of Postgraduate Medicine 01-11-1985
Oxford University Press
BMJ Group
Subjects:
Adult
Creatinine - metabolism
Female
Fetal Membranes, Premature Rupture - blood
Gentamicins - blood
Half-Life
Humans
Pelvic Inflammatory Disease - blood
Pregnancy
Online Access:Get full text
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Summary:The serum half-life of gentamicin following an intravenous dose was compared between 19 pregnant women (28-34 weeks of pregnancy) with premature rupture of the membranes and 17 non-pregnant women with pelvic inflammatory disease, the groups being age and weight matched. A significant reduction of gentamicin half-life was found in the pregnant group.
Bibliography:istex:B69158F756399FBD72E9C9FBF0A9ED9BF9F23E56
PMID:4070116
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href:postgradmedj-61-979.pdf
local:postgradmedj;61/721/979
ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0032-5473
1469-0756
DOI:10.1136/pgmj.61.721.979