Human papillomavirus PCR direct sequencing study of cervical precancerous lesions in Quebec children

• Published in: Sexually transmitted infections Vol. 77; no. 5; p. 391
• Main Authors: Oligny, Luc L, Feoli-Fonseca, Juan Carlos, Brochu, Pierre, Simard, Pierre, Falconi, Sarah, Yotov, Wagner V
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Ltd 01-10-2001; BMJ Publishing Group LTD; BMJ Group
• Subjects: Adolescent; Adults; Age; Cervical cancer; cervical intraepithelial neoplasia; Cervical Intraepithelial Neoplasia - pathology; Cervical Intraepithelial Neoplasia - virology; children; Children & youth; Female; Human papillomavirus; Humans; Letter to the Editor; Papillomaviridae - genetics; Papillomavirus Infections - diagnosis; Papillomavirus Infections - prevention & control; Polymerase Chain Reaction - methods; Precancerous Conditions - pathology; Precancerous Conditions - virology; Quebec; Tumor Virus Infections - diagnosis; Tumor Virus Infections - prevention & control; Uterine Cervical Neoplasms - pathology; Uterine Cervical Neoplasms - virology; Vaccines; Quebec; Quebec Canada
• ISSN: 1368-4973; 1472-3263
• DOI: 10.1136/sti.77.5.391

In the group of cervical biopsies from adolescent girls with CIN (n = 36, age 14-17), as well as in the larger control group of adult women (n = 487, age 18-72), the percentage of high risk HPV types increased, and the low risk HPV types decreased with the progression from low grade (CIN-I) to high grade (CIN-II and III) precancerous lesions.