Targeting Nrf2 in Protection Against Renal Disease

Renal disease is a serious health problem, with increasing incidence and prevalence. Oxidative stress and inflammation play a key role in the pathogenesis and progression of renal disease. Therefore, therapeutic approaches to decrease oxidative stress should be of interest. This review aims to provi...

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Bibliographic Details
Published in:	Current medicinal chemistry Vol. 24; no. 33; p. 3583
Main Authors:	Guerrero-Hue, Melania, Farre-Alins, Victor, Palomino-Antolin, Alejandra, Parada, Esther, Rubio-Navarro, Alfonso, Egido, Jesus, Egea, Javier, Moreno, Juan A
Format:	Journal Article
Language:	English
Published:	Netherlands 01-01-2017
Subjects:	Acute Kidney Injury - drug therapy Acute Kidney Injury - genetics Acute Kidney Injury - metabolism Acute Kidney Injury - pathology Animals Drug Discovery Gene Expression Regulation - drug effects Humans Inflammation - drug therapy Inflammation - genetics Inflammation - metabolism Inflammation - pathology Kidney - drug effects Kidney - metabolism Kidney - pathology Molecular Targeted Therapy NF-E2-Related Factor 2 - agonists NF-E2-Related Factor 2 - genetics NF-E2-Related Factor 2 - metabolism Oxidative Stress - drug effects Renal Insufficiency, Chronic - drug therapy Renal Insufficiency, Chronic - genetics Renal Insufficiency, Chronic - metabolism Renal Insufficiency, Chronic - pathology Signal Transduction - drug effects oxidation acute and chronic kidney injury Nrf2 inflammation therapy renal damage
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