Organisational and financial consequences of the early discharge of patients treated for acute bacterial skin and skin structure infection and osteomyelitis in infectious disease departments in Greece, Italy and Spain: a scenario analysis

ObjectiveThe aim of the analysis is to assess the organisational and economic consequences of adopting an early discharge strategy for the treatment of acute bacterial skin and skin structure infection (ABSSSI) and osteomyelitis within infectious disease departments.SettingInfectious disease departm...

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Published in:BMJ open Vol. 9; no. 9; p. e031356
Main Authors: Restelli, Umberto, Bonfanti, Marzia, Croce, Davide, Grau, Santiago, Metallidis, Symeon, Moreno Guillén, Santiago, Pacelli, Valeria, Rizzardini, Giuliano, Soro, Marco, Vozikis, Athanasios, Gray, Alastair
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Abstract ObjectiveThe aim of the analysis is to assess the organisational and economic consequences of adopting an early discharge strategy for the treatment of acute bacterial skin and skin structure infection (ABSSSI) and osteomyelitis within infectious disease departments.SettingInfectious disease departments in Greece, Italy and Spain.ParticipantsNo patients were involved in the analysis performed.InterventionsAn analytic framework was developed to consider two alternative scenarios: standard hospitalisation care or an early discharge strategy for patients hospitalised due to ABSSSI and osteomyelitis, from the perspective of the National Health Services of Greece, Italy and Spain. The variables considered were: the number of annual hospitalisations eligible for early discharge, the antibiotic treatments considered (ie, oral antibiotics and intravenous long-acting antibiotics), diagnosis-related group (DRG) reimbursements, number of days of hospitalisation, incidence and costs of hospital-acquired infections, additional follow-up visits and intravenous administrations. Data were based on published literature and expert opinions.Primary and secondary outcome measuresNumber of days of hospitalisation avoided and direct medical costs avoided.ResultsThe total number of days of hospitalisation avoided on a yearly basis would be between 2216 and 5595 in Greece (−8/−21 hospital beds), between 15 848 and 38 444 in Italy (−57/−135 hospital beds) and between 7529 and 23 520 in Spain (−27/−85 hospital beds). From an economic perspective, the impact of the early discharge scenario is a reduction between €45 036 and €149 552 in Greece, a reduction between €182 132 and €437 990 in Italy and a reduction between €292 284 and €884 035 in Spain.ConclusionsThe early discharge strategy presented would have a positive organisational impact on National Health Services, leading to potential savings in beds, and to a reduction of hospital-acquired infections and costs.
AbstractList ObjectiveThe aim of the analysis is to assess the organisational and economic consequences of adopting an early discharge strategy for the treatment of acute bacterial skin and skin structure infection (ABSSSI) and osteomyelitis within infectious disease departments.SettingInfectious disease departments in Greece, Italy and Spain.ParticipantsNo patients were involved in the analysis performed.InterventionsAn analytic framework was developed to consider two alternative scenarios: standard hospitalisation care or an early discharge strategy for patients hospitalised due to ABSSSI and osteomyelitis, from the perspective of the National Health Services of Greece, Italy and Spain. The variables considered were: the number of annual hospitalisations eligible for early discharge, the antibiotic treatments considered (ie, oral antibiotics and intravenous long-acting antibiotics), diagnosis-related group (DRG) reimbursements, number of days of hospitalisation, incidence and costs of hospital-acquired infections, additional follow-up visits and intravenous administrations. Data were based on published literature and expert opinions.Primary and secondary outcome measuresNumber of days of hospitalisation avoided and direct medical costs avoided.ResultsThe total number of days of hospitalisation avoided on a yearly basis would be between 2216 and 5595 in Greece (−8/−21 hospital beds), between 15 848 and 38 444 in Italy (−57/−135 hospital beds) and between 7529 and 23 520 in Spain (−27/−85 hospital beds). From an economic perspective, the impact of the early discharge scenario is a reduction between €45 036 and €149 552 in Greece, a reduction between €182 132 and €437 990 in Italy and a reduction between €292 284 and €884 035 in Spain.ConclusionsThe early discharge strategy presented would have a positive organisational impact on National Health Services, leading to potential savings in beds, and to a reduction of hospital-acquired infections and costs.
OBJECTIVEThe aim of the analysis is to assess the organisational and economic consequences of adopting an early discharge strategy for the treatment of acute bacterial skin and skin structure infection (ABSSSI) and osteomyelitis within infectious disease departments. SETTINGInfectious disease departments in Greece, Italy and Spain. PARTICIPANTSNo patients were involved in the analysis performed. INTERVENTIONSAn analytic framework was developed to consider two alternative scenarios: standard hospitalisation care or an early discharge strategy for patients hospitalised due to ABSSSI and osteomyelitis, from the perspective of the National Health Services of Greece, Italy and Spain. The variables considered were: the number of annual hospitalisations eligible for early discharge, the antibiotic treatments considered (ie, oral antibiotics and intravenous long-acting antibiotics), diagnosis-related group (DRG) reimbursements, number of days of hospitalisation, incidence and costs of hospital-acquired infections, additional follow-up visits and intravenous administrations. Data were based on published literature and expert opinions. PRIMARY AND SECONDARY OUTCOME MEASURESNumber of days of hospitalisation avoided and direct medical costs avoided. RESULTSThe total number of days of hospitalisation avoided on a yearly basis would be between 2216 and 5595 in Greece (-8/-21 hospital beds), between 15 848 and 38 444 in Italy (-57/-135 hospital beds) and between 7529 and 23 520 in Spain (-27/-85 hospital beds). From an economic perspective, the impact of the early discharge scenario is a reduction between €45 036 and €149 552 in Greece, a reduction between €182 132 and €437 990 in Italy and a reduction between €292 284 and €884 035 in Spain. CONCLUSIONSThe early discharge strategy presented would have a positive organisational impact on National Health Services, leading to potential savings in beds, and to a reduction of hospital-acquired infections and costs.
The aim of the analysis is to assess the organisational and economic consequences of adopting an early discharge strategy for the treatment of acute bacterial skin and skin structure infection (ABSSSI) and osteomyelitis within infectious disease departments. Infectious disease departments in Greece, Italy and Spain. No patients were involved in the analysis performed. An analytic framework was developed to consider two alternative scenarios: standard hospitalisation care or an early discharge strategy for patients hospitalised due to ABSSSI and osteomyelitis, from the perspective of the National Health Services of Greece, Italy and Spain. The variables considered were: the number of annual hospitalisations eligible for early discharge, the antibiotic treatments considered (ie, oral antibiotics and intravenous long-acting antibiotics), diagnosis-related group (DRG) reimbursements, number of days of hospitalisation, incidence and costs of hospital-acquired infections, additional follow-up visits and intravenous administrations. Data were based on published literature and expert opinions. Number of days of hospitalisation avoided and direct medical costs avoided. The total number of days of hospitalisation avoided on a yearly basis would be between 2216 and 5595 in Greece (-8/-21 hospital beds), between 15 848 and 38 444 in Italy (-57/-135 hospital beds) and between 7529 and 23 520 in Spain (-27/-85 hospital beds). From an economic perspective, the impact of the early discharge scenario is a reduction between €45 036 and €149 552 in Greece, a reduction between €182 132 and €437 990 in Italy and a reduction between €292 284 and €884 035 in Spain. The early discharge strategy presented would have a positive organisational impact on National Health Services, leading to potential savings in beds, and to a reduction of hospital-acquired infections and costs.
Author Grau, Santiago
Moreno Guillén, Santiago
Vozikis, Athanasios
Restelli, Umberto
Gray, Alastair
Bonfanti, Marzia
Rizzardini, Giuliano
Metallidis, Symeon
Croce, Davide
Pacelli, Valeria
Soro, Marco
AuthorAffiliation 6 Department of Infectious Diseases , ASST Fatebenefratelli Sacco University Hospital , Milan , Italy
7 School of Clinical Medicine, Faculty of Health Sciences , University of the Witwatersrand , Johannesburg , South Africa
9 Laboratory of Health Economics and Management , University of Piraeus , Piraeus , Greece
4 Medical School of Aristotle University of Thessaloniki , Thessaloniki , Greece
5 Department of Infectious Diseases , Hospital Ramón y Cajal, University of Alcalá , Madrid , Spain
10 Health Economics Research Centre, Nuffield Department of Population Health , University of Oxford , Oxford , UK
8 Global HEOR , Angelini , Roma , Lazio , Italy
2 School of Public Health, Faculty of Health Sciences , University of the Witwatersrand , Johannesburg , South Africa
1 Center for Health Economics, Social and Health Care Management , LIUC–Università Cattaneo , Castellanza , Italy
3 Pharmacy Department , Hospital del Mar , Barcelona , Spain
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/31515433$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1136/emj.20.2.149
10.1136/bmjopen-2014-004879
10.1108/14777260710732259
10.1086/420939
10.1093/jac/dks194
10.1016/j.jhin.2017.01.017
10.1093/jac/dkm210
10.1016/j.ijantimicag.2017.02.017
10.1080/17843286.2018.1424503
10.1016/j.ijantimicag.2017.03.016
10.1093/jac/dkx123
10.1016/j.ejim.2016.07.030
10.1016/j.healthpol.2017.07.005
10.2807/1560-7917.ES.2016.21.46.30399
10.1071/AH09821
10.1016/j.ijantimicag.2014.04.007
10.1016/S0140-6736(13)60102-6
10.1056/NEJMhpr020557
10.1016/S1198-743X(16)30095-7
10.1086/512642
10.7861/clinmedicine.12-4-346
10.1093/jac/dkp343
10.1186/cc13821
10.1016/S0014-2565(02)71118-1
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Issue 9
Keywords Hospital acquired infection
Hospital beds
Infectious Diseases
Organisation
Economic evaluation
Language English
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References Graves, Weinhold, Tong 2007; 28
McKee, Karanikolos, Belcher 2012; 12
González-Ramallo, Mirón-Rubio, Mujal 2017; 50
Proudlove, Gordon, Boaden 2003; 20
Burke 2003; 348
Chapman, Dixon, Andrews 2009; 64
Russo, Concia, Cristini 2016; 22
Tice, Rehm, Dalovisio 2004; 38
Weist, Högberg, Diaz Högberg 2016; 21
Scott 2010; 34
Wolkewitz, Cooper, Palomar-Martinez 2014; 18
Wenzl, Naci, Mossialos 2017; 121
Karanikolos, Mladovsky, Cylus 2013; 381
Morano Amado, Del Campo Pérez, López Miragaya 2002; 202
Gray, Dryden, Charos 2012; 67
Vargas-Palacios, Meads, Twiddy 2017; 72
Gianino, Vallino, Minniti 2007; 21
Rutberg, Borgstedt Risberg, Sjödahl 2014; 4
Matthews, Conlon, Berendt 2007; 60
Palmieri, Alberici, Deales 2013; 21
Ottolini, Buggio, Somigliana 2016; 36
Eckmann, Lawson, Nathwani 2014; 44
Wolkewitz, Zortel, Palomar-Martinez 2017; 96
Smismans, Vantrappen, Verbiest 2018; 73
Durojaiye, Bell, Andrews 2018; 51
Rutberg (2024052014542283000_9.9.e031356.11) 2014; 4
2024052014542283000_9.9.e031356.29
2024052014542283000_9.9.e031356.26
2024052014542283000_9.9.e031356.27
Palmieri (2024052014542283000_9.9.e031356.34) 2013; 21
Vargas-Palacios (2024052014542283000_9.9.e031356.17) 2017; 72
Wolkewitz (2024052014542283000_9.9.e031356.8) 2017; 96
González-Ramallo (2024052014542283000_9.9.e031356.33) 2017; 50
2024052014542283000_9.9.e031356.13
2024052014542283000_9.9.e031356.14
2024052014542283000_9.9.e031356.12
2024052014542283000_9.9.e031356.31
2024052014542283000_9.9.e031356.10
2024052014542283000_9.9.e031356.32
2024052014542283000_9.9.e031356.30
2024052014542283000_9.9.e031356.19
2024052014542283000_9.9.e031356.3
2024052014542283000_9.9.e031356.15
2024052014542283000_9.9.e031356.16
Scott (2024052014542283000_9.9.e031356.6) 2010; 34
2024052014542283000_9.9.e031356.9
2024052014542283000_9.9.e031356.4
2024052014542283000_9.9.e031356.5
Morano Amado (2024052014542283000_9.9.e031356.28) 2002; 202
Ottolini (2024052014542283000_9.9.e031356.2) 2016; 36
2024052014542283000_9.9.e031356.7
Wenzl (2024052014542283000_9.9.e031356.1) 2017; 121
Smismans (2024052014542283000_9.9.e031356.18) 2018; 73
2024052014542283000_9.9.e031356.24
2024052014542283000_9.9.e031356.25
2024052014542283000_9.9.e031356.22
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References_xml – volume: 20
  start-page: 149
  year: 2003
  article-title: Can good bed management solve the overcrowding in accident and emergency departments?
  publication-title: Emerg Med J
  doi: 10.1136/emj.20.2.149
  contributor:
    fullname: Boaden
– volume: 202
  start-page: 476
  year: 2002
  article-title: [Nosocomial bacteremia in the adult patient. Study of associated costs]
  publication-title: Rev Clin Esp
  contributor:
    fullname: López Miragaya
– volume: 4
  year: 2014
  article-title: Characterisations of adverse events detected in a university hospital: a 4-year study using the global trigger tool method
  publication-title: BMJ Open
  doi: 10.1136/bmjopen-2014-004879
  contributor:
    fullname: Sjödahl
– volume: 21
  start-page: 39
  year: 2007
  article-title: A model for calculating costs of hospital-acquired infections: an Italian experience
  publication-title: J Health Organ Manag
  doi: 10.1108/14777260710732259
  contributor:
    fullname: Minniti
– volume: 38
  start-page: 1651
  year: 2004
  article-title: Practice guidelines for outpatient parenteral antimicrobial therapy. IDSA guidelines
  publication-title: Clin Infect Dis
  doi: 10.1086/420939
  contributor:
    fullname: Dalovisio
– volume: 67
  start-page: 2297
  year: 2012
  article-title: Antibiotic management and early discharge from Hospital: an economic analysis
  publication-title: J Antimicrob Chemother
  doi: 10.1093/jac/dks194
  contributor:
    fullname: Charos
– volume: 96
  start-page: 81
  year: 2017
  article-title: Landmark prediction of nosocomial infection risk to disentangle short- and long-stay patients
  publication-title: J Hosp Infect
  doi: 10.1016/j.jhin.2017.01.017
  contributor:
    fullname: Palomar-Martinez
– volume: 60
  start-page: 356
  year: 2007
  article-title: Outpatient parenteral antimicrobial therapy (OPAT): is it safe for selected patients to self-administer at home? A retrospective analysis of a large cohort over 13 years
  publication-title: J Antimicrob Chemother
  doi: 10.1093/jac/dkm210
  contributor:
    fullname: Berendt
– volume: 50
  start-page: 114
  year: 2017
  article-title: Costs of outpatient parenteral antimicrobial therapy (OPAT) administered by hospital at home units in Spain
  publication-title: Int J Antimicrob Agents
  doi: 10.1016/j.ijantimicag.2017.02.017
  contributor:
    fullname: Mujal
– volume: 73
  start-page: 257
  year: 2018
  article-title: OPAT: proof of concept in a peripheral Belgian hospital after review of the literature
  publication-title: Acta Clin Belg
  doi: 10.1080/17843286.2018.1424503
  contributor:
    fullname: Verbiest
– volume: 51
  start-page: 26
  year: 2018
  article-title: Clinical efficacy, cost analysis and patient acceptability of outpatient parenteral antibiotic therapy (OPAT): a decade of Sheffield (UK) OPAT service
  publication-title: Int J Antimicrob Agents
  doi: 10.1016/j.ijantimicag.2017.03.016
  contributor:
    fullname: Andrews
– volume: 72
  start-page: 2392
  year: 2017
  article-title: Cost-Effectiveness of outpatient parenteral antibiotic therapy: a simulation modelling approach
  publication-title: J Antimicrob Chemother
  doi: 10.1093/jac/dkx123
  contributor:
    fullname: Twiddy
– volume: 36
  start-page: 1
  year: 2016
  article-title: The complex interface between economy and healthcare: an introductory overview for clinicians
  publication-title: Eur J Intern Med
  doi: 10.1016/j.ejim.2016.07.030
  contributor:
    fullname: Somigliana
– volume: 121
  start-page: 947
  year: 2017
  article-title: Health policy in times of austerity-A conceptual framework for evaluating effects of policy on efficiency and equity illustrated with examples from Europe since 2008
  publication-title: Health Policy
  doi: 10.1016/j.healthpol.2017.07.005
  contributor:
    fullname: Mossialos
– volume: 21
  year: 2016
  article-title: Ecdc publishes 2015 surveillance data on antimicrobial resistance and antimicrobial consumption in Europe
  publication-title: Euro Surveill
  doi: 10.2807/1560-7917.ES.2016.21.46.30399
  contributor:
    fullname: Diaz Högberg
– volume: 34
  start-page: 317
  year: 2010
  article-title: Public hospital bed crisis: too few or too misused?
  publication-title: Aust Health Rev
  doi: 10.1071/AH09821
  contributor:
    fullname: Scott
– volume: 44
  start-page: 56
  year: 2014
  article-title: Antibiotic treatment patterns across Europe in patients with complicated skin and soft-tissue infections due to meticillin-resistant Staphylococcus aureus: a plea for implementation of early switch and early discharge criteria
  publication-title: Int J Antimicrob Agents
  doi: 10.1016/j.ijantimicag.2014.04.007
  contributor:
    fullname: Nathwani
– volume: 381
  start-page: 1323
  year: 2013
  article-title: Financial crisis, austerity, and health in Europe
  publication-title: Lancet
  doi: 10.1016/S0140-6736(13)60102-6
  contributor:
    fullname: Cylus
– volume: 348
  start-page: 651
  year: 2003
  article-title: Infection control - a problem for patient safety
  publication-title: N Engl J Med
  doi: 10.1056/NEJMhpr020557
  contributor:
    fullname: Burke
– volume: 22
  start-page: S27
  issue: Suppl 2
  year: 2016
  article-title: Current and future trends in antibiotic therapy of acute bacterial skin and skin-structure infections
  publication-title: Clin Microbiol Infect
  doi: 10.1016/S1198-743X(16)30095-7
  contributor:
    fullname: Cristini
– volume: 28
  start-page: 280
  year: 2007
  article-title: Effect of healthcare-acquired infection on length of hospital stay and cost
  publication-title: Infect Control Hosp Epidemiol
  doi: 10.1086/512642
  contributor:
    fullname: Tong
– volume: 12
  start-page: 346
  year: 2012
  article-title: Austerity: a failed experiment on the people of Europe
  publication-title: Clin Med
  doi: 10.7861/clinmedicine.12-4-346
  contributor:
    fullname: Belcher
– volume: 64
  start-page: 1316
  year: 2009
  article-title: Clinical efficacy and cost-effectiveness of outpatient parenteral antibiotic therapy (OPAT): a UK perspective
  publication-title: J Antimicrob Chemother
  doi: 10.1093/jac/dkp343
  contributor:
    fullname: Andrews
– volume: 18
  year: 2014
  article-title: Multilevel competing risk models to evaluate the risk of nosocomial infection
  publication-title: Crit Care
  doi: 10.1186/cc13821
  contributor:
    fullname: Palomar-Martinez
– volume: 21
  start-page: 270
  year: 2013
  article-title: Early discharge of infectious disease patients: an opportunity or extra cost for the Italian healthcare system?
  publication-title: Infez Med
  contributor:
    fullname: Deales
– ident: 2024052014542283000_9.9.e031356.5
  doi: 10.1136/emj.20.2.149
– ident: 2024052014542283000_9.9.e031356.29
– volume: 21
  start-page: 270
  year: 2013
  ident: 2024052014542283000_9.9.e031356.34
  article-title: Early discharge of infectious disease patients: an opportunity or extra cost for the Italian healthcare system?
  publication-title: Infez Med
  contributor:
    fullname: Palmieri
– ident: 2024052014542283000_9.9.e031356.31
– ident: 2024052014542283000_9.9.e031356.13
  doi: 10.2807/1560-7917.ES.2016.21.46.30399
– volume: 73
  start-page: 257
  year: 2018
  ident: 2024052014542283000_9.9.e031356.18
  article-title: OPAT: proof of concept in a peripheral Belgian hospital after review of the literature
  publication-title: Acta Clin Belg
  doi: 10.1080/17843286.2018.1424503
  contributor:
    fullname: Smismans
– volume: 202
  start-page: 476
  year: 2002
  ident: 2024052014542283000_9.9.e031356.28
  article-title: [Nosocomial bacteremia in the adult patient. Study of associated costs]
  publication-title: Rev Clin Esp
  doi: 10.1016/S0014-2565(02)71118-1
  contributor:
    fullname: Morano Amado
– volume: 121
  start-page: 947
  year: 2017
  ident: 2024052014542283000_9.9.e031356.1
  article-title: Health policy in times of austerity-A conceptual framework for evaluating effects of policy on efficiency and equity illustrated with examples from Europe since 2008
  publication-title: Health Policy
  doi: 10.1016/j.healthpol.2017.07.005
  contributor:
    fullname: Wenzl
– volume: 96
  start-page: 81
  year: 2017
  ident: 2024052014542283000_9.9.e031356.8
  article-title: Landmark prediction of nosocomial infection risk to disentangle short- and long-stay patients
  publication-title: J Hosp Infect
  doi: 10.1016/j.jhin.2017.01.017
  contributor:
    fullname: Wolkewitz
– ident: 2024052014542283000_9.9.e031356.14
  doi: 10.1093/jac/dkp343
– ident: 2024052014542283000_9.9.e031356.21
– volume: 34
  start-page: 317
  year: 2010
  ident: 2024052014542283000_9.9.e031356.6
  article-title: Public hospital bed crisis: too few or too misused?
  publication-title: Aust Health Rev
  doi: 10.1071/AH09821
  contributor:
    fullname: Scott
– ident: 2024052014542283000_9.9.e031356.25
  doi: 10.1186/cc13821
– ident: 2024052014542283000_9.9.e031356.32
  doi: 10.1016/j.ijantimicag.2017.03.016
– ident: 2024052014542283000_9.9.e031356.4
  doi: 10.7861/clinmedicine.12-4-346
– volume: 72
  start-page: 2392
  year: 2017
  ident: 2024052014542283000_9.9.e031356.17
  article-title: Cost-Effectiveness of outpatient parenteral antibiotic therapy: a simulation modelling approach
  publication-title: J Antimicrob Chemother
  doi: 10.1093/jac/dkx123
  contributor:
    fullname: Vargas-Palacios
– ident: 2024052014542283000_9.9.e031356.23
  doi: 10.1016/j.ijantimicag.2014.04.007
– ident: 2024052014542283000_9.9.e031356.15
  doi: 10.1093/jac/dkm210
– ident: 2024052014542283000_9.9.e031356.30
– ident: 2024052014542283000_9.9.e031356.3
  doi: 10.1016/S0140-6736(13)60102-6
– volume: 50
  start-page: 114
  year: 2017
  ident: 2024052014542283000_9.9.e031356.33
  article-title: Costs of outpatient parenteral antimicrobial therapy (OPAT) administered by hospital at home units in Spain
  publication-title: Int J Antimicrob Agents
  doi: 10.1016/j.ijantimicag.2017.02.017
  contributor:
    fullname: González-Ramallo
– ident: 2024052014542283000_9.9.e031356.26
– ident: 2024052014542283000_9.9.e031356.12
  doi: 10.1086/512642
– ident: 2024052014542283000_9.9.e031356.24
– ident: 2024052014542283000_9.9.e031356.16
  doi: 10.1086/420939
– ident: 2024052014542283000_9.9.e031356.27
  doi: 10.1108/14777260710732259
– ident: 2024052014542283000_9.9.e031356.10
  doi: 10.1056/NEJMhpr020557
– ident: 2024052014542283000_9.9.e031356.20
– volume: 4
  year: 2014
  ident: 2024052014542283000_9.9.e031356.11
  article-title: Characterisations of adverse events detected in a university hospital: a 4-year study using the global trigger tool method
  publication-title: BMJ Open
  doi: 10.1136/bmjopen-2014-004879
  contributor:
    fullname: Rutberg
– volume: 36
  start-page: 1
  year: 2016
  ident: 2024052014542283000_9.9.e031356.2
  article-title: The complex interface between economy and healthcare: an introductory overview for clinicians
  publication-title: Eur J Intern Med
  doi: 10.1016/j.ejim.2016.07.030
  contributor:
    fullname: Ottolini
– ident: 2024052014542283000_9.9.e031356.9
– ident: 2024052014542283000_9.9.e031356.22
– ident: 2024052014542283000_9.9.e031356.19
  doi: 10.1016/S1198-743X(16)30095-7
– ident: 2024052014542283000_9.9.e031356.7
  doi: 10.1093/jac/dks194
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Snippet ObjectiveThe aim of the analysis is to assess the organisational and economic consequences of adopting an early discharge strategy for the treatment of acute...
The aim of the analysis is to assess the organisational and economic consequences of adopting an early discharge strategy for the treatment of acute bacterial...
OBJECTIVEThe aim of the analysis is to assess the organisational and economic consequences of adopting an early discharge strategy for the treatment of acute...
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StartPage e031356
SubjectTerms Antibiotics
Bacterial infections
Budgets
Costs
Disease prevention
Efficiency
Hospitals
Infectious Diseases
Nosocomial infections
Patients
Sovereign debt
Title Organisational and financial consequences of the early discharge of patients treated for acute bacterial skin and skin structure infection and osteomyelitis in infectious disease departments in Greece, Italy and Spain: a scenario analysis
URI https://bmjopen.bmj.com/content/9/9/e031356.full
https://www.ncbi.nlm.nih.gov/pubmed/31515433
https://www.proquest.com/docview/2290037628
https://search.proquest.com/docview/2290906569
https://pubmed.ncbi.nlm.nih.gov/PMC6747647
Volume 9
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