Modulation of the Drug Resistance by Platonia insignis Mart. Extract, Ethyl Acetate Fraction and Morelloflavone/Volkensiflavone (Biflavonoids) in Staphylococcus aureus Strains Overexpressing Efflux Pump Genes

Microbial resistance to antibiotics is a global public health problem, which requires urgent attention. Platonia insignis is a native species from the eastern Brazilian Amazon, used in the treatment of burns and wounds. To evaluate the antimicrobial activity of the hydroalcoholic extract of P. insig...

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Bibliographic Details
Published in:	Current drug metabolism Vol. 22; no. 2; p. 114
Main Authors:	E Silva, Andressa K F, Dos Reis, Antonielly C, Pinheiro, Emanuelly E A, de Sousa, Jonas N, de Alcântara Oliveira, Felipe A, Moura, Arkellau K S, de Sousa L Neto, José, das Graças L Citó, Antonia M, Siqueira-Júnior, José P, Kaatz, Glenn W, Barreto, Humberto M
Format:	Journal Article
Language:	English
Published:	Netherlands 01-01-2021
Subjects:	Anti-Bacterial Agents - pharmacology Bacterial Proteins - antagonists & inhibitors Bacterial Proteins - metabolism Biflavonoids - pharmacology Clusiaceae Drug Resistance - drug effects Drug Resistance - physiology Flowers Microbial Sensitivity Tests Plant Extracts - pharmacology Staphylococcus aureus - drug effects Staphylococcus aureus - metabolism resistance to antibiotics antimicrobial activity modulation of the drug resistance Platonia insignis efflux pumps Staphylococcus aureus
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