β-cell development and turnover during prenatal life in humans

Introductionβ-cell regeneration is an area under active investigation for the future treatment of diabetes, but little is known about the patterns and dynamics of prenatal β-cell development in humans. In particular, the quantitative changes in β-cell mass in the developing pancreas have not been el...

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Bibliographic Details
Published in:	European journal of endocrinology Vol. 162; no. 3; pp. 559 - 568
Main Authors:	Meier, Juris J, Köhler, Christina U, Alkhatib, Bacel, Sergi, Consolato, Junker, Theresa, Klein, Harald H, Schmidt, Wolfgang E, Fritsch, Helga
Format:	Journal Article
Language:	English
Published:	Bristol BioScientifica 01-03-2010 European Society of Endocrinology
Subjects:	Apoptosis - physiology Biological and medical sciences Cell Differentiation - physiology Cell Division - physiology Cell Proliferation Clinical Study Endocrinopathies Female Fundamental and applied biological sciences. Psychology Glucagon - metabolism Humans Immunohistochemistry Insulin - metabolism Insulin-Secreting Cells - cytology Insulin-Secreting Cells - metabolism Islets of Langerhans - embryology Islets of Langerhans - metabolism Male Medical sciences Microscopy, Fluorescence Pancreas - embryology Pancreas - metabolism Vertebrates: endocrinology Human Cell proliferation Prenatal Langerhans islet Turnover β Cell Endocrinology Endocrine pancreas
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