Trichomonal vaginitis. A 24-hr regimen of nimorazole compared with a 7-day regimen of metronidazole

A 24-hr regimen of nimorazole (1 g. orally at 12-hrly intervals for three doses) was compared with metronidazole (200 mg. three times daily for 7 days) in the treatment of trichomonal vaginitis. The two treatment schedules were given to alternate patients, pregnant women being excluded. One hundred...

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Bibliographic Details
Published in:	British journal of venereal diseases Vol. 51; no. 1; pp. 54 - 56
Main Author:	Wigfield, A S
Format:	Journal Article
Language:	English
Published:	England BMJ Publishing Group Ltd 01-02-1975 BMJ Publishing Group LTD
Subjects:	Administration, Oral Clinical Trials as Topic Female Humans Male Metronidazole - administration & dosage Metronidazole - therapeutic use Nimorazole - administration & dosage Nimorazole - therapeutic use Nitroimidazoles - therapeutic use Trichomonas Vaginitis - drug therapy
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Summary:	A 24-hr regimen of nimorazole (1 g. orally at 12-hrly intervals for three doses) was compared with metronidazole (200 mg. three times daily for 7 days) in the treatment of trichomonal vaginitis. The two treatment schedules were given to alternate patients, pregnant women being excluded. One hundred cases were treated on each schedule; roughly one-fifth of the patients in each group defaulted. There were no observed failures with either schedule. The reasons for these exceptionally good results are discussed.
Bibliography:	ark:/67375/NVC-QDG9P7TP-4 PMID:1092425 istex:462049E4E7D92AFB59D42E196945216AB2F0D870 href:sextrans-51-54.pdf local:sextrans;51/1/54 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23
ISSN:	0007-134X 1472-3263
DOI:	10.1136/sti.51.1.54