Non-neoplastic colorectal disease biopsies: evaluation and differential diagnosis

A wide variety of non-neoplastic conditions may be encountered on colorectal biopsy encompassing idiopathic, infectious, vascular and immune-mediated aetiologies. Although interpretation of such biopsies may be challenging, appreciation of the dominant pattern of injury and subsequent host response...

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Bibliographic Details
Published in:	Journal of clinical pathology Vol. 73; no. 12; p. 783
Main Authors:	Moore, Michelle, Feakins, Roger M, Lauwers, Gregory Y
Format:	Journal Article
Language:	English
Published:	England 01-12-2020
Subjects:	Diagnosis, Differential Humans Intestinal Diseases - diagnosis Intestinal Diseases - pathology inflammatory bowel diseases colon colitis
Online Access:	Get more information
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Summary:	A wide variety of non-neoplastic conditions may be encountered on colorectal biopsy encompassing idiopathic, infectious, vascular and immune-mediated aetiologies. Although interpretation of such biopsies may be challenging, appreciation of the dominant pattern of injury and subsequent host response may allow for a more focused histological diagnosis in the correct clinical and endoscopic setting. This article aims to provide a systematic, methodical approach to the assessment of such biopsies, concentrating mainly on diagnoses other than inflammatory bowel disease.
ISSN:	1472-4146
DOI:	10.1136/jclinpath-2020-206794