Use of planar array electrophysiology for the development of robust ion channel cell lines

The tractability of ion channels as drug targets has been significantly improved by the advent of planar array electrophysiology platforms which have dramatically increased the capacity for electrophysiological profiling of lead series compounds. However, the data quality and through-put obtained wi...

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Bibliographic Details

Published in:	Combinatorial chemistry & high throughput screening Vol. 12; no. 1; p. 96
Main Authors:	Clare, Jeffrey J, Chen, Mao Xiang, Downie, David L, Trezise, Derek J, Powell, Andrew J
Format:	Journal Article
Language:	English
Published:	United Arab Emirates 01-01-2009
Subjects:	Cell Line - cytology Drug Discovery - methods Electrophysiology - instrumentation Electrophysiology - methods Humans Ion Channels Tissue Array Analysis
Online Access:	Get more information
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