A disclosed diagnosis for 24 year’s unknown illness

IgG4-related disease (IgG4-RD) is a newly described illness over the last several years. A 57-year-old man, who had been followed for chronic kidney disease (CKD), chronic pancreatitis and history of operated cholangitis, was admitted to our hospital for abdominal pain and worsening renal function....

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Published in:BMJ case reports Vol. 2017; p. bcr-2017-221317
Main Authors: Hanai, Shogo, Kinjo, Kazushi, Uezato, Madoka, Tokuda, Yasuharu
Format: Journal Article
Language:English
Published: England BMJ Publishing Group LTD 20-12-2017
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Series:Case Report
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Abstract IgG4-related disease (IgG4-RD) is a newly described illness over the last several years. A 57-year-old man, who had been followed for chronic kidney disease (CKD), chronic pancreatitis and history of operated cholangitis, was admitted to our hospital for abdominal pain and worsening renal function. Serum levels of IgG and IgG4 were elevated. CT scan showed the characteristic findings of IgG4-related retroperitoneal fibrosis, pancreas and kidney disease. An endoscopic biopsy revealed the finding compatible with IgG4-RD. Steroid therapy led to the remission of his abdominal pain. Patients with CKD of unknown aetiology may have IgG4-RD.
AbstractList IgG4-related disease (IgG4-RD) is a newly described illness over the last several years. A 57-year-old man, who had been followed for chronic kidney disease (CKD), chronic pancreatitis and history of operated cholangitis, was admitted to our hospital for abdominal pain and worsening renal function. Serum levels of IgG and IgG4 were elevated. CT scan showed the characteristic findings of IgG4-related retroperitoneal fibrosis, pancreas and kidney disease. An endoscopic biopsy revealed the finding compatible with IgG4-RD. Steroid therapy led to the remission of his abdominal pain. Patients with CKD of unknown aetiology may have IgG4-RD.
Author Uezato, Madoka
Kinjo, Kazushi
Tokuda, Yasuharu
Hanai, Shogo
AuthorAffiliation 2 Internal Medicine , Nakagami General Hospital , Okinawa , Okinawa , Japan
1 Department of Internal Medicine , Nakagami General Hospital , Okinawa , Japan
3 Department of General Internal Medicine , Tsukuba University , Mito , Ibaraki , Japan
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  givenname: Kazushi
  surname: Kinjo
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  givenname: Madoka
  surname: Uezato
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  fullname: Tokuda, Yasuharu
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  organization: Department of General Internal Medicine, Tsukuba University, Mito, Ibaraki, Japan
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10.1097/MPA.0b013e3182480c99
10.1007/s10067-017-3685-7
10.1007/s00535-003-1175-y
10.1056/NEJM200103083441005
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Keywords Chronic Renal Failure
Pancreatitis
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Kamisawa, Funata, Hayashi 2003; 38
Xia, Fan, Liu 2017
Hamano, Kawa, Horiuchi 2001; 344
Kamisawa, Zen, Pillai 2015; 385
Kanno (key-10.1136/bcr-2017-221317-3) 2012; 41
Hamano (key-10.1136/bcr-2017-221317-1) 2001; 344
Xia (key-10.1136/bcr-2017-221317-4) 2017
Kamisawa (key-10.1136/bcr-2017-221317-5) 2015; 385
Kamisawa (key-10.1136/bcr-2017-221317-2) 2003; 38
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Snippet IgG4-related disease (IgG4-RD) is a newly described illness over the last several years. A 57-year-old man, who had been followed for chronic kidney disease...
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SubjectTerms Abdomen
Abdominal Pain - diagnosis
Abdominal Pain - etiology
Anti-Inflammatory Agents - therapeutic use
Australasia
Autoimmune diseases
Autoimmune Diseases - diagnosis
Biopsy
Case reports
Cholangitis - diagnosis
Cholangitis - physiopathology
Chronic illnesses
Diagnosis, Differential
Endoscopy
Epidemiology
Family medical history
Fatal Outcome
Female
Histology
Humans
Immunoglobulin G - blood
Kidney diseases
Male
Medical diagnosis
Medical imaging
Middle Aged
New Disease
Pain
Pancreatic cancer
Pancreatitis
Pancreatitis, Chronic - diagnosis
Pancreatitis, Chronic - physiopathology
Patients
Prednisolone - therapeutic use
Retroperitoneal Fibrosis - diagnosis
Retroperitoneal Fibrosis - physiopathology
Stroke
Time Factors
Tomography, X-Ray Computed
Tumors
White
Title A disclosed diagnosis for 24 year’s unknown illness
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