Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions

• Published in: Antimicrobial Agents and Chemotherapy Vol. 41; no. 10; pp. 2132 - 2136
• Main Authors: SHINABARGER, D. L, MAROTTI, K. R, MURRAY, R. W, LIN, A. H, MELCHIOR, E. P, SWANEY, S. M, DUNYAK, D. S, DEMYAN, W. F, BUYSSE, J. M
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01-10-1997
• Subjects: Acetamides; Acetamides - pharmacology; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents - pharmacology; Antibacterial agents; Antibiotics. Antiinfectious agents. Antiparasitic agents; Bacterial Proteins - biosynthesis; Biological and medical sciences; Coliphages; Culture Media; Escherichia coli - drug effects; Escherichia coli - genetics; Linezolid; Medical sciences; Microbial Sensitivity Tests; N-Formylmethionine - metabolism; Oxazoles; Oxazoles - pharmacology; Oxazolidinones; Pharmacology. Drug treatments; Poly U - metabolism; Polyribosomes - drug effects; Polyribosomes - metabolism; Protein Biosynthesis; Protein Biosynthesis - drug effects; Ribosomes - drug effects; Ribosomes - metabolism; Transcription, Genetic - drug effects; Antibiotic; Escherichia coli; Bacteria; Protein synthesis inhibitor; Translation inhibitor; Antibacterial agent; Mechanism of action; In vitro; Enterobacteriaceae
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/aac.41.10.2132

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