Pentostam induces resistance to antimony and the preservative chlorocresol in Leishmania donovani promastigotes and axenically grown amastigotes

• Published in: Antimicrobial Agents and Chemotherapy Vol. 41; no. 5; pp. 1064 - 1068
• Main Authors: EPHROS, M, WALDMAN, E, ZILBERSTEIN, D
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01-05-1997
• Subjects: Animals; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antimony - pharmacology; Antimony Sodium Gluconate; Antimony Sodium Gluconate - pharmacology; Antiparasitic agents; Antiprotozoal Agents; Antiprotozoal Agents - pharmacology; Biological and medical sciences; Cells, Cultured; Cresols - pharmacology; Dose-Response Relationship, Drug; Drug Resistance; Leishmania donovani; Leishmania donovani - drug effects; Leishmania donovani - growth & development; Medical sciences; Pharmacology. Drug treatments; Research Support, Non-U.S. Gov't; Kinetoplastida; Protozoa; Axenic culture; Enzyme; Leishmania donovani; Sodium stibogluconate; Lyases; Ornithine decarboxylase; In vitro; Biological activity; Resistance; Antimony V; Chlorocresol; Carbon-carbon lyases; Preservative; Carboxy-lyases; Parasiticid; Amastigote; Promastigote
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/aac.41.5.1064

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