In-Depth Characterization of Full-Length Archived Viral Genomes after Nine Years of Posttreatment HIV Control

In the search for control of human immunodeficiency virus type 1 (HIV-1) infection without antiretroviral therapy, posttreatment controllers (PTCs) are models of HIV remission. To better understand their mechanisms of control, we characterized the HIV blood reservoirs of 8 PTCs (median of 9.4 years...

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Bibliographic Details
Published in:	Microbiology spectrum Vol. 11; no. 1; p. e0326722
Main Authors:	Trémeaux, Pauline, Lemoine, Frédéric, Mélard, Adeline, Gousset, Marine, Boufassa, Faroudy, Orr, Sylvie, Monceaux, Valérie, Gascuel, Olivier, Lambotte, Olivier, Hocqueloux, Laurent, Saez-Cirion, Asier, Rouzioux, Christine, Avettand-Fenoel, Véronique
Format:	Journal Article
Language:	English
Published:	United States American Society for Microbiology 14-02-2023
Subjects:	CD4-Positive T-Lymphocytes defective proviruses Genome, Viral HIV Infections HIV reservoirs HIV-1 - genetics Humans Leukocytes, Mononuclear Life Sciences next-generation sequencing posttreatment HIV controller posttreatment HIV controllers provirus Proviruses - genetics Research Article Viral Load Virology HIV reservoirs ultradeep sequencing provirus next-generation sequencing proviruses defective proviruses posttreatment HIV controller posttreatment HIV controllers
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