Phase II Trial of Doxorubicin Plus Escalated High-Dose Ifosfamide in Patients With Advanced Soft Tissue Sarcomas of the Adult: A Study of the Spanish Group for Research on Sarcomas (GEIS)

Background. To explore the tolerance and the activity of high-dose ifosfamide (IFOS) combined with doxorubicin (DXR) at 50 mg/m(2) every 4 weeks in patients with soft tissue sarcomas. Methods. DXR was given IV bolus and IFOS by continuous infusion at 2 g/m(2)/day. Initial IFOS dose (12 g/m(2)) was a...

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Bibliographic Details
Published in:Sarcoma Vol. 2006; pp. 18 - 25
Main Authors: Buesa, J.M, Garcia del Muro, J, Cruz, J, Montalar, J, Escudero, P, Martin, J, Maurel, J, Lopez-Pousa, A, de las Penas, R, Casado, A
Format: Journal Article
Language:English
Published: Egypt Hindawi Limiteds 2006
John Wiley & Sons, Inc
Hindawi Publishing Corporation
Hindawi Limited
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