Biosynthesis of an Anti-Addiction Agent from the Iboga Plant

(−)-Ibogaine and (−)-voacangine are plant derived psychoactives that show promise as treatments for opioid addiction. However, these compounds are produced by hard to source plants, making these chemicals difficult for broad-scale use. Here we report the complete biosynthesis of (−)-voacangine, and...

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Bibliographic Details

Published in:	Journal of the American Chemical Society Vol. 141; no. 33; pp. 12979 - 12983
Main Authors:	Farrow, Scott C, Kamileen, Mohamed O, Caputi, Lorenzo, Bussey, Kate, Mundy, Julia E. A, McAtee, Rory C, Stephenson, Corey R. J, O’Connor, Sarah E
Format:	Journal Article
Language:	English
Published:	United States American Chemical Society 21-08-2019
Subjects:	Communication
Online Access:	Get full text
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