Biosynthetic Polymers as Functional Materials

The synthesis of functional polymers encoded with biomolecules has been an extensive area of research for decades. As such, a diverse toolbox of polymerization techniques and bioconjugation methods has been developed. The greatest impact of this work has been in biomedicine and biotechnology, where...

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Published in:Macromolecules Vol. 49; no. 12; pp. 4379 - 4394
Main Authors: Carlini, Andrea S, Adamiak, Lisa, Gianneschi, Nathan C
Format: Journal Article
Language:English
Published: United States American Chemical Society 28-06-2016
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Abstract The synthesis of functional polymers encoded with biomolecules has been an extensive area of research for decades. As such, a diverse toolbox of polymerization techniques and bioconjugation methods has been developed. The greatest impact of this work has been in biomedicine and biotechnology, where fully synthetic and naturally derived biomolecules are used cooperatively. Despite significant improvements in biocompatible and functionally diverse polymers, our success in the field is constrained by recognized limitations in polymer architecture control, structural dynamics, and biostabilization. This Perspective discusses the current status of functional biosynthetic polymers and highlights innovative strategies reported within the past five years that have made great strides in overcoming the aforementioned barriers.
AbstractList The synthesis of functional polymers encoded with biomolecules has been an extensive area of research for decades. As such, a diverse toolbox of polymerization techniques and bioconjugation methods has been developed. The greatest impact of this work has been in biomedicine and biotechnology, where fully synthetic and naturally derived biomolecules are used cooperatively. Despite significant improvements in biocompatible and functionally diverse polymers, our success in the field is constrained by recognized limitations in polymer architecture control, structural dynamics, and biostabilization. This Perspective discusses the current status of functional biosynthetic polymers and highlights innovative strategies reported within the past five years that have made great strides in overcoming the aforementioned barriers.
The synthesis of functional polymers encoded with biomolecules has been an extensive area of research for decades. As such, a diverse toolbox of polymerization techniques and bioconjugation methods has been developed. The greatest impact of this work has been in biomedicine and biotechnology, where fully synthetic and naturally derived biomolecules are used cooperatively. Despite significant improvements in biocompatible and functionally diverse polymers, our success in the field is constrained by recognized limitations in polymer architecture control, structural dynamics, and biostabilization. This Perspective discusses the current status of functional biosynthetic polymers and highlights innovative strategies reported within the past five years that have made great strides in overcoming the aforementioned barriers.
Author Carlini, Andrea S
Gianneschi, Nathan C
Adamiak, Lisa
AuthorAffiliation Department of Chemistry and Biochemistry
University of California, San Diego
AuthorAffiliation_xml – name: University of California, San Diego
– name: Department of Chemistry and Biochemistry
Author_xml – sequence: 1
  givenname: Andrea S
  surname: Carlini
  fullname: Carlini, Andrea S
– sequence: 2
  givenname: Lisa
  surname: Adamiak
  fullname: Adamiak, Lisa
– sequence: 3
  givenname: Nathan C
  surname: Gianneschi
  fullname: Gianneschi, Nathan C
  email: ngianneschi@ucsd.edu
BackLink https://www.ncbi.nlm.nih.gov/pubmed/27375299$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1002/adma.201404059
10.1002/smll.200901728
10.1039/C3PY01536J
10.1021/la300563s
10.1021/ma400869e
10.1002/adhm.201200071
10.1021/ja309044z
10.1021/acs.biomac.5b00623
10.1038/ncomms7295
10.1039/C4PY01503G
10.1295/polymj.26.1019
10.1021/ja5088216
10.1021/nl5002313
10.1021/bm301844u
10.1021/acs.nanolett.5b00699
10.1021/acs.biomac.5b00153
10.1021/bm5001839
10.1021/nn503719n
10.1016/j.actbio.2014.07.020
10.1124/dmd.114.058347
10.1002/marc.201300205
10.1021/ma4022983
10.1038/nchem.1573
10.1002/anie.201308366
10.1021/ja402262x
10.1021/ma901561t
10.1021/ma501384q
10.1016/j.jare.2013.07.006
10.1038/nbt0910-917
10.1002/marc.201400072
10.1021/acs.biomac.5b01287
10.1021/ma301303b
10.1021/ma5015534
10.1021/acs.macromol.5b01795
10.1021/acsmacrolett.5b00606
10.1039/C4TB00775A
10.1002/anie.200603064
10.1021/acs.biomac.5b00680
10.1021/ma501386v
10.1073/pnas.1508599112
10.1021/bm5002608
10.1021/acs.macromol.5b01058
10.1073/pnas.1015862108
10.1002/macp.1984.020061984119
10.1021/ja507889x
10.1517/17425247.2015.961420
10.1073/pnas.1408035111
10.1038/nmat4106
10.7150/thno.11139
10.1016/j.jconrel.2014.03.052
10.1002/adhm.201500403
10.1002/(SICI)1099-0518(20000615)38:12<2121::AID-POLA10>3.0.CO;2-X
10.1039/C5SM00865D
10.1039/C5PY01765C
10.1002/9783527636150.ch4
10.1021/ja510147n
10.1021/ma200799b
10.1021/ma5009918
10.1002/adfm.201401502
10.1021/ab500050m
10.1002/anie.201412206
10.1002/adma.201502003
10.1002/smll.201502730
10.1021/acs.macromol.5b00178
10.1021/ma401175m
10.1039/C3PY01338C
10.1021/la047570n
10.1021/acs.chemrev.5b00346
10.1517/17425240903380446
10.1002/adma.201501803
10.1039/C4BM00448E
10.1007/s00396-015-3562-3
10.1002/anie.200902672
10.1002/adhm.201500334
10.1021/bm5006195
10.1016/j.addr.2011.03.014
10.1021/ar200148z
10.1016/j.actbio.2012.08.035
10.1073/pnas.1323829111
10.1021/cb400828a
10.1021/acsmacrolett.5b00460
10.1038/382607a0
10.1038/nmat4037
10.1016/0040-6090(92)90417-A
10.1039/c3cc40472b
10.1021/ja503142s
10.1126/scitranslmed.3006557
10.1002/marc.201500042
10.1021/ja111346c
10.1021/ja503598z
10.1039/C5CC07882B
10.1002/jbm.a.33305
10.1002/jbm.a.35178
10.1038/nchem.2346
10.1016/j.jcis.2015.01.060
10.1021/jacs.5b06969
10.1038/1781168a0
10.1002/adma.200501612
10.1039/c3py00901g
10.1021/acs.macromol.5b01908
10.1073/pnas.1201122109
10.1586/erd.11.27
10.1002/1615-4169(200208)344:6/7<634::AID-ADSC634>3.0.CO;2-K
10.1021/acs.biomac.5b00855
10.1021/mz4002673
10.1021/nl2025882
10.5966/sctm.2014-0049
10.1021/mz300535r
10.1021/ja408182p
10.1039/c3cs90057f
10.1073/pnas.1216375110
10.1021/cr200157d
10.1016/B978-1-78242-105-4.00001-8
10.1021/acs.biomac.5b00795
10.1039/c3sc52964a
10.1021/ma501007j
10.1021/jacs.5b05497
10.1021/jacs.5b05903
10.1038/nature12806
10.1002/anie.201300068
10.1038/nmat3949
10.1021/ja207005z
10.1021/bm501449a
10.1021/jacs.5b04940
10.1038/nature08693
10.1021/acs.chemrev.5b00292
10.1007/s00264-006-0276-7
10.1016/j.biomaterials.2013.12.009
10.1021/ja512073m
10.1021/bm1005799
10.1039/C5PY00121H
10.1021/nn305030g
10.1021/ja203375n
10.1021/ja506379s
10.1021/acsmacrolett.5b00018
10.3109/1061186X.2010.512470
10.1002/pola.25927
10.1021/cr068415b
10.1021/ar2003144
10.1002/anie.201300293
10.1021/ja00897a025
10.1021/bm200519y
10.1002/adfm.201303699
10.1002/marc.201000507
10.1039/C5RA14325J
10.1021/ja5080486
10.1039/C5PY00028A
10.1021/ma902749q
10.1021/ja408754z
10.1021/bm401634r
10.1002/mabi.200900080
10.1002/anie.201412391
10.1021/ja308620h
10.1021/ja500372u
10.1016/j.msec.2014.01.052
10.1002/marc.201100881
10.1039/c3py00526g
10.1039/C5TB01370D
10.1021/acs.macromol.5b01426
10.1039/C4TB00496E
10.1039/C4PY01560F
10.1021/acs.macromol.5b00846
10.1002/adma.201300823
10.1021/bm501456g
10.1002/adma.201202343
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References ref45/cit45
ref99/cit99
ref3/cit3
ref81/cit81
ref16/cit16
ref52/cit52
ref114/cit114
ref23/cit23
ref115/cit115
ref110/cit110
Reece J. B. (ref26/cit26) 2014
ref111/cit111
ref2/cit2
ref112/cit112
ref77/cit77
ref113/cit113
ref71/cit71
ref117/cit117
ref20/cit20
ref48/cit48
ref118/cit118
ref74/cit74
ref119/cit119
ref10/cit10
ref35/cit35
ref89/cit89
ref19/cit19
ref93/cit93
ref42/cit42
ref96/cit96
ref107/cit107
ref120/cit120
ref109/cit109
ref13/cit13
ref122/cit122
ref105/cit105
ref61/cit61
ref67/cit67
ref38/cit38
ref128/cit128
ref90/cit90
ref124/cit124
ref64/cit64
ref126/cit126
ref54/cit54
ref18/cit18
ref136/cit136
ref137/cit137
ref65/cit65
ref97/cit97
ref101/cit101
ref11/cit11
ref102/cit102
ref29/cit29
ref76/cit76
ref86/cit86
ref32/cit32
ref39/cit39
Günay K. A. (ref1/cit1) 2012
ref5/cit5
ref43/cit43
ref80/cit80
ref133/cit133
ref28/cit28
ref132/cit132
ref91/cit91
ref148/cit148
ref55/cit55
ref144/cit144
ref12/cit12
ref163/cit163
ref66/cit66
ref22/cit22
ref121/cit121
ref33/cit33
ref87/cit87
ref106/cit106
ref140/cit140
ref129/cit129
ref44/cit44
ref70/cit70
ref98/cit98
ref125/cit125
ref9/cit9
ref152/cit152
ref153/cit153
ref154/cit154
ref150/cit150
ref63/cit63
ref151/cit151
ref56/cit56
ref159/cit159
ref92/cit92
ref155/cit155
ref156/cit156
ref157/cit157
ref158/cit158
ref8/cit8
ref31/cit31
ref59/cit59
ref85/cit85
ref34/cit34
ref37/cit37
ref60/cit60
ref88/cit88
ref17/cit17
ref82/cit82
ref147/cit147
ref160/cit160
ref143/cit143
ref53/cit53
ref145/cit145
Poole-Warren L. A. (ref6/cit6) 2016
ref21/cit21
ref166/cit166
Dvir T. (ref300/cit300) 2011; 11
ref149/cit149
ref162/cit162
ref46/cit46
ref164/cit164
ref49/cit49
ref75/cit75
Wang L. (ref200/cit200) 2015; 5
García-Borrón J. C. (ref27/cit27) 2011
ref24/cit24
ref141/cit141
ref50/cit50
ref78/cit78
ref36/cit36
ref83/cit83
ref138/cit138
ref79/cit79
ref139/cit139
ref100/cit100
ref25/cit25
ref103/cit103
ref72/cit72
ref14/cit14
ref57/cit57
ref51/cit51
ref134/cit134
Urquhart J. (ref116/cit116) 2014
ref135/cit135
ref40/cit40
ref68/cit68
ref94/cit94
ref130/cit130
ref131/cit131
ref146/cit146
ref161/cit161
ref142/cit142
ref73/cit73
ref69/cit69
ref165/cit165
ref15/cit15
ref62/cit62
ref41/cit41
ref58/cit58
ref95/cit95
ref108/cit108
ref104/cit104
ref4/cit4
ref30/cit30
ref47/cit47
ref84/cit84
ref127/cit127
ref123/cit123
ref7/cit7
References_xml – ident: ref156/cit156
  doi: 10.1002/adma.201404059
– ident: ref144/cit144
  doi: 10.1002/smll.200901728
– ident: ref56/cit56
  doi: 10.1039/C3PY01536J
– ident: ref143/cit143
  doi: 10.1021/la300563s
– ident: ref39/cit39
  doi: 10.1021/ma400869e
– ident: ref4/cit4
  doi: 10.1002/adhm.201200071
– ident: ref120/cit120
  doi: 10.1021/ja309044z
– ident: ref83/cit83
  doi: 10.1021/acs.biomac.5b00623
– ident: ref109/cit109
  doi: 10.1038/ncomms7295
– ident: ref51/cit51
  doi: 10.1039/C4PY01503G
– ident: ref111/cit111
  doi: 10.1295/polymj.26.1019
– ident: ref78/cit78
  doi: 10.1021/ja5088216
– ident: ref98/cit98
  doi: 10.1021/nl5002313
– ident: ref122/cit122
  doi: 10.1021/bm301844u
– ident: ref100/cit100
  doi: 10.1021/acs.nanolett.5b00699
– ident: ref128/cit128
  doi: 10.1021/acs.biomac.5b00153
– ident: ref154/cit154
  doi: 10.1021/bm5001839
– ident: ref110/cit110
  doi: 10.1021/nn503719n
– ident: ref127/cit127
  doi: 10.1016/j.actbio.2014.07.020
– ident: ref131/cit131
  doi: 10.1124/dmd.114.058347
– ident: ref15/cit15
  doi: 10.1002/marc.201300205
– ident: ref34/cit34
  doi: 10.1021/ma4022983
– volume-title: Chemistry World
  year: 2014
  ident: ref116/cit116
  contributor:
    fullname: Urquhart J.
– ident: ref159/cit159
  doi: 10.1038/nchem.1573
– volume-title: Campbell Biology
  year: 2014
  ident: ref26/cit26
  contributor:
    fullname: Reece J. B.
– ident: ref91/cit91
  doi: 10.1002/anie.201308366
– ident: ref54/cit54
  doi: 10.1021/ja402262x
– ident: ref24/cit24
  doi: 10.1021/ma901561t
– ident: ref40/cit40
  doi: 10.1021/ma501384q
– ident: ref103/cit103
  doi: 10.1016/j.jare.2013.07.006
– ident: ref130/cit130
  doi: 10.1038/nbt0910-917
– ident: ref28/cit28
  doi: 10.1002/marc.201400072
– ident: ref112/cit112
  doi: 10.1021/acs.biomac.5b01287
– ident: ref37/cit37
  doi: 10.1021/ma301303b
– ident: ref29/cit29
  doi: 10.1021/ma5015534
– ident: ref33/cit33
  doi: 10.1021/acs.macromol.5b01795
– ident: ref65/cit65
  doi: 10.1021/acsmacrolett.5b00606
– ident: ref101/cit101
  doi: 10.1039/C4TB00775A
– ident: ref160/cit160
  doi: 10.1002/anie.200603064
– ident: ref10/cit10
  doi: 10.1021/acs.biomac.5b00680
– ident: ref13/cit13
  doi: 10.1021/ma501386v
– ident: ref89/cit89
  doi: 10.1073/pnas.1508599112
– ident: ref157/cit157
  doi: 10.1021/bm5002608
– ident: ref62/cit62
  doi: 10.1021/acs.macromol.5b01058
– ident: ref123/cit123
  doi: 10.1073/pnas.1015862108
– ident: ref166/cit166
  doi: 10.1002/macp.1984.020061984119
– ident: ref66/cit66
  doi: 10.1021/ja507889x
– ident: ref139/cit139
  doi: 10.1517/17425247.2015.961420
– ident: ref152/cit152
  doi: 10.1073/pnas.1408035111
– ident: ref12/cit12
  doi: 10.1038/nmat4106
– volume: 5
  start-page: 787
  issue: 8
  year: 2015
  ident: ref200/cit200
  publication-title: Theranostics
  doi: 10.7150/thno.11139
  contributor:
    fullname: Wang L.
– ident: ref94/cit94
  doi: 10.1016/j.jconrel.2014.03.052
– ident: ref146/cit146
  doi: 10.1002/adhm.201500403
– ident: ref45/cit45
  doi: 10.1002/(SICI)1099-0518(20000615)38:12<2121::AID-POLA10>3.0.CO;2-X
– ident: ref16/cit16
  doi: 10.1039/C5SM00865D
– ident: ref42/cit42
  doi: 10.1039/C5PY01765C
– start-page: 87
  volume-title: Melanins and Melanosomes
  year: 2011
  ident: ref27/cit27
  doi: 10.1002/9783527636150.ch4
  contributor:
    fullname: García-Borrón J. C.
– ident: ref5/cit5
  doi: 10.1021/ja510147n
– ident: ref19/cit19
  doi: 10.1021/ma200799b
– ident: ref25/cit25
  doi: 10.1021/ma5009918
– ident: ref117/cit117
  doi: 10.1002/adfm.201401502
– ident: ref149/cit149
  doi: 10.1021/ab500050m
– ident: ref46/cit46
  doi: 10.1002/anie.201412206
– start-page: 1
  volume-title: Functional Polymers by Post-Polymerization Modification
  year: 2012
  ident: ref1/cit1
  contributor:
    fullname: Günay K. A.
– ident: ref97/cit97
  doi: 10.1002/adma.201502003
– ident: ref96/cit96
  doi: 10.1002/smll.201502730
– ident: ref49/cit49
  doi: 10.1021/acs.macromol.5b00178
– ident: ref53/cit53
  doi: 10.1021/ma401175m
– ident: ref75/cit75
  doi: 10.1039/C3PY01338C
– ident: ref145/cit145
  doi: 10.1021/la047570n
– ident: ref158/cit158
  doi: 10.1021/acs.chemrev.5b00346
– ident: ref161/cit161
  doi: 10.1517/17425240903380446
– ident: ref76/cit76
  doi: 10.1002/adma.201501803
– ident: ref134/cit134
  doi: 10.1039/C4BM00448E
– ident: ref86/cit86
  doi: 10.1007/s00396-015-3562-3
– ident: ref155/cit155
  doi: 10.1002/anie.200902672
– ident: ref136/cit136
  doi: 10.1002/adhm.201500334
– ident: ref132/cit132
  doi: 10.1021/bm5006195
– ident: ref93/cit93
  doi: 10.1016/j.addr.2011.03.014
– ident: ref17/cit17
  doi: 10.1021/ar200148z
– ident: ref129/cit129
  doi: 10.1016/j.actbio.2012.08.035
– ident: ref148/cit148
  doi: 10.1073/pnas.1323829111
– ident: ref14/cit14
  doi: 10.1021/cb400828a
– ident: ref44/cit44
  doi: 10.1021/acsmacrolett.5b00460
– ident: ref162/cit162
  doi: 10.1038/382607a0
– ident: ref124/cit124
  doi: 10.1038/nmat4037
– ident: ref140/cit140
  doi: 10.1016/0040-6090(92)90417-A
– ident: ref72/cit72
  doi: 10.1039/c3cc40472b
– ident: ref73/cit73
  doi: 10.1021/ja503142s
– ident: ref119/cit119
  doi: 10.1126/scitranslmed.3006557
– ident: ref47/cit47
  doi: 10.1002/marc.201500042
– ident: ref55/cit55
  doi: 10.1021/ja111346c
– ident: ref165/cit165
  doi: 10.1021/ja503598z
– ident: ref74/cit74
  doi: 10.1039/C5CC07882B
– ident: ref147/cit147
  doi: 10.1002/jbm.a.33305
– ident: ref151/cit151
  doi: 10.1002/jbm.a.35178
– ident: ref88/cit88
  doi: 10.1038/nchem.2346
– ident: ref150/cit150
  doi: 10.1016/j.jcis.2015.01.060
– ident: ref23/cit23
  doi: 10.1021/jacs.5b06969
– ident: ref30/cit30
  doi: 10.1038/1781168a0
– ident: ref102/cit102
  doi: 10.1002/adma.200501612
– ident: ref32/cit32
  doi: 10.1039/c3py00901g
– ident: ref52/cit52
  doi: 10.1021/acs.macromol.5b01908
– ident: ref105/cit105
  doi: 10.1073/pnas.1201122109
– ident: ref115/cit115
  doi: 10.1586/erd.11.27
– ident: ref59/cit59
  doi: 10.1002/1615-4169(200208)344:6/7<634::AID-ADSC634>3.0.CO;2-K
– ident: ref18/cit18
  doi: 10.1021/acs.biomac.5b00855
– ident: ref60/cit60
  doi: 10.1021/mz4002673
– volume: 11
  start-page: 4411
  issue: 10
  year: 2011
  ident: ref300/cit300
  publication-title: Nano Letters
  doi: 10.1021/nl2025882
  contributor:
    fullname: Dvir T.
– ident: ref104/cit104
  doi: 10.5966/sctm.2014-0049
– ident: ref68/cit68
  doi: 10.1021/mz300535r
– ident: ref80/cit80
  doi: 10.1021/ja408182p
– ident: ref3/cit3
  doi: 10.1039/c3cs90057f
– ident: ref8/cit8
  doi: 10.1073/pnas.1216375110
– ident: ref138/cit138
  doi: 10.1021/cr200157d
– start-page: 3
  volume-title: Biosynthetic Polymers for Medical Applications
  year: 2016
  ident: ref6/cit6
  doi: 10.1016/B978-1-78242-105-4.00001-8
  contributor:
    fullname: Poole-Warren L. A.
– ident: ref85/cit85
  doi: 10.1021/acs.biomac.5b00795
– ident: ref113/cit113
  doi: 10.1039/c3sc52964a
– ident: ref36/cit36
  doi: 10.1021/ma501007j
– ident: ref61/cit61
  doi: 10.1021/jacs.5b05497
– ident: ref43/cit43
  doi: 10.1021/jacs.5b05903
– ident: ref108/cit108
  doi: 10.1038/nature12806
– ident: ref31/cit31
  doi: 10.1002/anie.201300068
– ident: ref71/cit71
  doi: 10.1038/nmat3949
– ident: ref11/cit11
  doi: 10.1021/ja207005z
– ident: ref35/cit35
  doi: 10.1021/bm501449a
– ident: ref67/cit67
  doi: 10.1021/jacs.5b04940
– ident: ref107/cit107
  doi: 10.1038/nature08693
– ident: ref57/cit57
  doi: 10.1021/acs.chemrev.5b00292
– ident: ref125/cit125
  doi: 10.1007/s00264-006-0276-7
– ident: ref153/cit153
  doi: 10.1016/j.biomaterials.2013.12.009
– ident: ref63/cit63
  doi: 10.1021/ja512073m
– ident: ref141/cit141
  doi: 10.1021/bm1005799
– ident: ref133/cit133
  doi: 10.1039/C5PY00121H
– ident: ref164/cit164
  doi: 10.1021/nn305030g
– ident: ref163/cit163
  doi: 10.1021/ja203375n
– ident: ref41/cit41
  doi: 10.1021/ja506379s
– ident: ref118/cit118
  doi: 10.1021/acsmacrolett.5b00018
– ident: ref135/cit135
  doi: 10.3109/1061186X.2010.512470
– ident: ref87/cit87
  doi: 10.1002/pola.25927
– ident: ref50/cit50
  doi: 10.1021/cr068415b
– ident: ref92/cit92
  doi: 10.1021/ar2003144
– ident: ref70/cit70
  doi: 10.1002/anie.201300293
– ident: ref64/cit64
  doi: 10.1021/ja00897a025
– ident: ref142/cit142
  doi: 10.1021/bm200519y
– ident: ref114/cit114
  doi: 10.1002/adfm.201303699
– ident: ref20/cit20
  doi: 10.1002/marc.201000507
– ident: ref137/cit137
  doi: 10.1039/C5RA14325J
– ident: ref9/cit9
  doi: 10.1021/ja5080486
– ident: ref48/cit48
  doi: 10.1039/C5PY00028A
– ident: ref69/cit69
  doi: 10.1021/ma902749q
– ident: ref21/cit21
  doi: 10.1021/ja408754z
– ident: ref84/cit84
  doi: 10.1021/bm401634r
– ident: ref106/cit106
  doi: 10.1002/mabi.200900080
– ident: ref38/cit38
  doi: 10.1002/anie.201412391
– ident: ref81/cit81
  doi: 10.1021/ja308620h
– ident: ref95/cit95
  doi: 10.1021/ja500372u
– ident: ref7/cit7
  doi: 10.1016/j.msec.2014.01.052
– ident: ref99/cit99
  doi: 10.1002/marc.201100881
– ident: ref79/cit79
  doi: 10.1039/c3py00526g
– ident: ref2/cit2
  doi: 10.1039/C5TB01370D
– ident: ref90/cit90
  doi: 10.1021/acs.macromol.5b01426
– ident: ref22/cit22
  doi: 10.1039/C4TB00496E
– ident: ref58/cit58
  doi: 10.1039/C4PY01560F
– ident: ref82/cit82
  doi: 10.1021/acs.macromol.5b00846
– ident: ref77/cit77
  doi: 10.1002/adma.201300823
– ident: ref121/cit121
  doi: 10.1021/bm501456g
– ident: ref126/cit126
  doi: 10.1002/adma.201202343
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Snippet The synthesis of functional polymers encoded with biomolecules has been an extensive area of research for decades. As such, a diverse toolbox of polymerization...
The synthesis of functional polymers encoded with biomolecules has been an extensive area of research for decades. As such, a diverse toolbox of polymerization...
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Title Biosynthetic Polymers as Functional Materials
URI http://dx.doi.org/10.1021/acs.macromol.6b00439
https://www.ncbi.nlm.nih.gov/pubmed/27375299
https://search.proquest.com/docview/1808677172
https://search.proquest.com/docview/1826718163
https://pubmed.ncbi.nlm.nih.gov/PMC4928144
Volume 49
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