The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin

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Bibliographic Details
Published in:	Antimicrobial Agents and Chemotherapy Vol. 41; no. 10; pp. 2127 - 2131
Main Authors:	LIN, A. H, MURRAY, R. W, VIDMAR, T. J, MAROTTI, K. R
Format:	Journal Article
Language:	English
Published:	Washington, DC American Society for Microbiology 01-10-1997
Subjects:	Acetamides Acetamides - metabolism Anti-Bacterial Agents Anti-Bacterial Agents - metabolism Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Chloramphenicol Chloramphenicol - metabolism Escherichia coli - metabolism Kinetics Lincomycin Lincomycin - metabolism Medical sciences Oxazoles Oxazoles - metabolism Oxazolidinones Pharmacology. Drug treatments Puromycin - pharmacology Ribosomes Ribosomes - metabolism Drug combination Ribosome Escherichia coli Chloramphenicol Molecular interaction Competitive inhibition Subunit In vitro Ribosomal protein Antibiotic Biological fixation Lincomycin Aminoglycoside Bacteria Drug interaction Protein synthesis inhibitor Antibacterial agent Mechanism of action Comparative study Enterobacteriaceae
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