Low-Molecular-Weight Heparin Use in a Case of Noncardiogenic Multifocal Perinatal Thromboembolic Stroke

A full-term neonate suffered multifocal cerebral infarctions due to multiple large vessel thrombi. Thrombophilia and cardiovascular assessments were negative, but due to the severity of the lesions and the concern for expansion of the thrombi or future embolic events, treatment with low-molecular-we...

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Bibliographic Details
Published in:Advances in hematology Vol. 2009; no. 2009; pp. 1 - 5
Main Authors: Tarquinio, Dan, Bennett, Jeffrey, Saxonhouse, Matthew A., Geyer, James D., Hunger, Stephen P., Smith, Amy, Carney, Paul R.
Format: Journal Article
Language:English
Published: Cairo, Egypt Hindawi Puplishing Corporation 2009
Hindawi Publishing Corporation
Hindawi Limited
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Summary:A full-term neonate suffered multifocal cerebral infarctions due to multiple large vessel thrombi. Thrombophilia and cardiovascular assessments were negative, but due to the severity of the lesions and the concern for expansion of the thrombi or future embolic events, treatment with low-molecular-weight heparin (LMWH) was initiated. No complications from treatment were experienced. We present this severe case in order to highlight difficult management decisions for newborns with multifocal perinatal thromboembolic stroke and to stress the need for further practice guidelines and research in this area.
Bibliography:Recommended by Charles S. Greenberg
ISSN:1687-9104
1687-9112
DOI:10.1155/2009/153643