Use of an In Vitro Pharmacodynamic Model To Derive a Linezolid Regimen That Optimizes Bacterial Kill and Prevents Emergence of Resistance in Bacillus anthracis

• Published in: Antimicrobial Agents and Chemotherapy Vol. 52; no. 7; pp. 2486 - 2496
• Main Authors: LOUIE, A, HEINE, H. S, KIM, K, BROWN, D. L, VANSCOY, B, LIU, W, KINZIG-SCHIPPERS, M, SÖRGEL, F, DRUSANO, G. L
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01-07-2008; American Society for Microbiology (ASM)
• Subjects: Acetamides; Acetamides - administration & dosage; Acetamides - pharmacokinetics; Acetamides - pharmacology; Anthrax - drug therapy; Anthrax - microbiology; Anthrax - prevention & control; Anti-Bacterial Agents; Anti-Bacterial Agents - administration & dosage; Anti-Bacterial Agents - pharmacokinetics; Anti-Bacterial Agents - pharmacology; Antibiotics. Antiinfectious agents. Antiparasitic agents; Bacillus anthracis; Bacillus anthracis - drug effects; Bacillus anthracis - genetics; Biological and medical sciences; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Bacterial - genetics; Humans; In Vitro Techniques; Linezolid; Medical sciences; Models, Biological; Monte Carlo Method; Mutation; Oxazolidinones; Oxazolidinones - administration & dosage; Oxazolidinones - pharmacokinetics; Oxazolidinones - pharmacology; Pharmacology. Drug treatments; Susceptibility; Linezolid; Bacillus anthracis; Pharmacodynamics; Bacillaceae; Epidemiology; In vitro; Biological activity; Infection; Prevention; Resistance; Antibiotic; Bacillales; Oxazolidinone derivative; Bacteriosis; Bacteria; Models; Protein synthesis inhibitor; Antibacterial agent; Therapeutic protocol; Oxazole derivatives
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.01439-07

Classifications
Services
AAC
Citing Articles
Google Scholar
PubMed
Related Content
Social Bookmarking
CiteULike
Delicious
Digg
Facebook
Google+
Mendeley
Reddit
StumbleUpon
Twitter
current issue
AAC
About
AAC
Subscribers
Authors
Reviewers
Advertisers
Inquiries from the Press
Permissions & Commercial Reprints
ASM Journals Public Access Policy
AAC
RSS Feeds
1752 N Street N.W. • Washington DC 20036
202.737.3600 • 202.942.9355 fax • [e-mail]
Print ISSN:
0066-4804
Online ISSN:
1098-6596
Copyright © 2014
by the
American Society for Microbiology.  
For an alternate route to
AAC
.asm.org, visit:
AAC