In Vitro and in Vivo Antiestrogenic Effects of Polycyclic Musks in Zebrafish

The polycyclic musks 6-acetyl-1,1,2,4,4,7-hexamethyltetraline (AHTN) and 1,2,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-γ-2-benzopyran (HHCB) are used as fragrance ingredients in perfumes, soaps, and household cleaning products. They are known to be ubiquitously present in the aquatic enviro...

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Bibliographic Details
Published in:	Environmental science & technology Vol. 38; no. 4; pp. 997 - 1002
Main Authors:	Schreurs, Richard H. M. M, Legler, Juliette, Artola-Garicano, Elsa, Sinnige, Theo L, Lanser, Peter H, Seinen, Willem, van der Burg, Bart
Format:	Journal Article
Language:	English
Published:	Washington, DC American Chemical Society 15-02-2004
Subjects:	Agnatha. Pisces Animal, plant and microbial ecology Animals Animals, Genetically Modified Applied ecology Benzopyrans - pharmacokinetics Benzopyrans - toxicity Biological and medical sciences Body Weight Cell Culture Techniques Danio rerio Dose-Response Relationship, Drug Ecotoxicology, biological effects of pollution Effects of pollution and side effects of pesticides on vertebrates Endocrine System - drug effects Estrogen Receptor Modulators - toxicity Estrogens Female Fish Freshwater Fundamental and applied biological sciences. Psychology Male Perfume Perfumes Pollutants Receptors, Estrogen - drug effects Tetrahydronaphthalenes - pharmacokinetics Tetrahydronaphthalenes - toxicity Water Pollutants, Chemical - pharmacokinetics Water Pollutants, Chemical - toxicity Water treatment Zebrafish Zebrafish - physiology Vertebrata Musk Pisces Biota Antiestrogen Polycyclic compound Water pollution Cyprinidae Biological effect Biological activity Contaminant
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