A General Protocol for Cu-Mediated Fluoro-deamination: Sandmeyer Fluorination of Diverse Aromatic Substrates

A Cu­(I)-mediated fluoro-deamination method for nucleophilic radiofluorination was devised. The method affords fluorinated aromatic products directly from anilines under both no-carrier added and stoichiometric conditions. Isolated radiochemical yields range from 11% to 81% with high radiochemical p...

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Bibliographic Details
Published in:Organic letters Vol. 23; no. 3; pp. 1011 - 1015
Main Authors: Pérez-García, R. Manuel, Grønnevik, Gaute, Riss, Patrick J
Format: Journal Article
Language:English
Published: United States American Chemical Society 05-02-2021
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