Interaction of a Histidine-Rich Antimicrobial Saliva Peptide with Model Cell Membranes: The Role of Histidines

Histatin 5 is a histidine-rich, intrinsically disordered, multifunctional saliva protein known to act as a first line of defense against oral candidiasis caused by Candida albicans. An earlier study showed that, upon interaction with a common model bilayer, a protein cushion spontaneously forms unde...

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Bibliographic Details

Published in:	Langmuir Vol. 39; no. 22; pp. 7694 - 7706
Main Authors:	Skog, Amanda E., Corucci, Giacomo, Tully, Mark D., Fragneto, Giovanna, Gerelli, Yuri, Skepö, Marie
Format:	Journal Article
Language:	English
Published:	United States American Chemical Society 06-06-2023
Subjects:	Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology Antimicrobial Peptides Biofysiks Biologi Biological Sciences Biophysics Cell Membrane - metabolism Histidine Lipid Bilayers - chemistry Natural Sciences Naturvetenskap Peptides Saliva - metabolism
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