Thermospray enhanced inductively coupled plasma atomic emission-spectroscopy detection for liquid chromatography

• Published in: Analytical chemistry (Washington) Vol. 62; no. 5; pp. 484 - 489
• Main Authors: Roychowdhury, S. B, Koropchak, John A
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 01-03-1990
• Subjects: 400102 - Chemical & Spectral Procedures; Analytical chemistry; ARSENIC; Chemistry; Chromatographic methods and physical methods associated with chromatography; CHROMATOGRAPHY; CHROMIUM; ELEMENTS; EMISSION SPECTROSCOPY; Exact sciences and technology; INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; LIQUID COLUMN CHROMATOGRAPHY; MEASURING INSTRUMENTS; MEASURING METHODS; METALS; Other chromatographic methods; SEMIMETALS; SEPARATION PROCESSES; SPECTROSCOPY; TRANSITION ELEMENTS; Technical progress; Chemical analysis; Coupled method; Liquid chromatography; Thermospray; Method; Inductive coupling plasma spectrometry; Emission spectrometry; Detection limit; Chromium; Nebulizer; Interface; Speciation; Flow injection
• ISSN: 0003-2700; 1520-6882
• DOI: 10.1021/ac00204a012

Thermospray sample introduction is studied as an interface between liquid chromatography and inductively coupled plasma atomic emission spectrometry for metal speciation studies. Detection limits for chromium species separated by ion chromatography or mobile phase ion-pairing chromatography are improved by factors of 24 and 36, respectively, for 50 and 25 {mu}m aperture based thermospray systems, as compared to pneumatic sample introduction. For arsenic species separated by ion chromatography, relative response factors between the two sample introduction systems were species dependent. Lower enhancements for certain species with thermospray were thought to result from thermal decomposition to form volatile species which were lost during desolvation. For nonaqueous size exclusion studies of organoiron species, detection limits were improved by a factor of about 50 with thermospray compared to a pneumatic sample introduction system.