Fruits are vehicles of drug-resistant pathogenic Candida tropicalis

• Published in: Microbiology spectrum Vol. 11; no. 6; p. e0147123
• Main Authors: Chen, Yin-Zhi, Tseng, Kuo-Yun, Wang, Si-Chong, Huang, Ciao-Lin, Lin, Chih-Chao, Zhou, Zi-Li, Tsai, De-Jiun, Lin, Chiao-Mei, Chen, Yu-Lian, Chen, Kai-Ting, Liao, Yu-Chieh, Chen, Feng-Jui, Sytwu, Huey-Kang, Lan, Chung-Yu, Lo, Hsiu-Jung
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 12-12-2023
• Subjects: Candida tropicalis; drug-resistance; environment; fruit; Mycology; Research Article; Candida tropicalis; drug-resistance; environment; fruit
• ISSN: 2165-0497; 2165-0497
• DOI: 10.1128/spectrum.01471-23

Of 123 identified isolates from the fruit surface,
was the most frequently found species, followed by
and
. All three fluconazole-resistant
were non-susceptible to voriconazole and belonged to the same predominant genotype of azole-resistant
causing candidemia in patients in Taiwan. Our findings provide evidence that fruit should be washed before eaten not only to remove chemicals but also potential drug-resistant pathogenic microbes, especially for immunocompromised individuals. To keep precious treatment options in patients, we not only continuously implement antimicrobial stewardship in hospitals but also reducing/stopping the use of agricultural fungicide classes used in human medicine.